Fig. 3.

MRI lesion outcomes of the CAMMS223 long-term follow-up cohort. Proportions of patients free of MRI disease activity, and of new MRI lesions (Gd-enhancing T1, new/enlarging T2 and new T1) from Year 7 to Year 12 (CAMMS03409 extension study enrollment until end of Year 12) in the long-term follow-up cohort. MRI outcomes were assessed annually from the CAMMS03409 extension study enrollment and onward, until end of Year 12. Freedom from MRI disease activity was defined as the absence of new gadolinium-enhancing T1 and new/enlarging T2 hyperintense lesions. Error bars denote 95% CIs. CI confidence interval, Gd gadolinium