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. 2020 Jun 18;267(11):3268–3273. doi: 10.1007/s00415-020-09969-z

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Case 3. Axial FLAIR images through the brain (a) demonstrating white matter changes over a 3-year interval. Coronal T1- and T2-weighted images through the brain (b) showing progressive atrophy of the brain over the 3-year interval. The most recent scan (right) shows bilateral medial temporal lobe atrophy, more so on the right. Amyloid PET imaging (c) was positive with loss of grey–white differentiation consistent with widespread amyloid deposition