Table 1.
QT interval prolongation targets with the chances to get affected by HCQ and/or AZM.
| Sr. No. | Targets affected by both HCQ and AZM | Targets affected by only HCQ | Targets affected by only AZM |
|---|---|---|---|
| 1 | LMNA | CACNA2D1 | F10 |
| 2 | KCNH2 | NOS1 | TSHR |
| 3 | ADRB1 | HSP90AA1 | PIK3CG |
| 4 | ADRB2 | CCND1 | HSP90B1 |
| 5 | ALB | NOS2 | DPP4 |
| 6 | SRC | CHKA | LGALS3 |
| 7 | ADRA2C | CDK2 | AKT1 |
| 8 | ELANE | HTR1A | ROCK1 |
| 9 | MC4R | HTR3A | LGALS4 |
| 10 | CYP1A2 | KIF11 | PDE4B |
| 11 | PRKCA | CYP2C8 | NPPA |
| 12 | EGFR | SPHK1 | DHFR |
| 13 | ESR1 | ROCK2 | NQO1 |
| 14 | PRKDC | SLC5A2 | |
| 15 | MMP9 | ITGA4 | |
| 16 | CYP2D6 | MLNR | |
| 17 | DRD2 | KDM1A | |
| 18 | CYP3A4 | TRAP1 | |
| 19 | MAPK14 | HTR4 | |
| 20 | ACHE | ||
| 21 | ABCB1 | ||
| 22 | SLC6A4 | ||
| 23 | CCR5 | ||
| 24 | HTR2A | ||
| 25 | CYP2C19 | ||
| 26 | CYP2C9 | ||
| 27 | HMGCR | ||
| 28 | INSR | ||
| 29 | CHRM3 | ||
| 30 | SYK | ||
| 31 | CYP2E1 | ||
| 32 | AKT3 | ||
| 33 | PDE5A | ||
| 34 | CDK4 | ||
| 35 | HRH1 | ||
| 36 | IGF1R | ||
| 37 | SLC6A2 | ||
| 38 | TACR1 | ||
| 39 | FYN | ||
| 40 | ADORA1 | ||
| 41 | AVPR1A |