Table 1.
Demographic, clinical, and laboratory parameters of responsive and nonresponsive patients with ulcerative colitis
| Response (n = 231) | No response or death (n = 32) | P value | |
|---|---|---|---|
| Age (years, median, IQR) | 37 (25, 47) | 31 (24.8, 40.5) | 0.057 |
| Male gender | 155/231 (67.1%) | 21/32 (65.6%) | 0.973 |
| Duration of episode (days, median, IQR) | 30 (15, 45) | 30 (20, 45) | 0.317 |
| Treatment | |||
| Oral steroid | 14 (6.1) | 0 (0) | 0.004 |
| Intravenous (IV) steroids | 211 (91.3) | 27 (84.4) | |
| IV steroid + cyclosporine | 4 (1.7) | 5 (15.6) | |
| Infliximab | 2 (0.9) | 0 (0) | |
| Death | 0 (0) | 4 (12.5) | <0.001 |
| Complications | |||
| None | 229 (99.1) | 13 (59.1) | <0.001 |
| Toxic megacolon | 2 (0.9) | 2 (9.1) | |
| Megacolon + perforation | 0 (0) | 3 (13.6) | |
| Septic shock | 0 (0) | 3 (13.6) | |
| Perforatopn | 0 (0) | 1 (4.5) | |
| Hb (g/dL, mean, SD) | 9.6 (2.6) | 8.6 (2) | 0.044 |
| Total leukocyte count (×109/mm3, median, IQR) | 8.4 (6.5, 11.1) | 7.9 (6, 10.9) | 0.516 |
| Polymorphonuclear leukocyte (%, median, IQR) | 76.5 (70, 84) | 78.5 (71.5, 84) | 0.455 |
| Platelet (×109/mm3, median, IQR) | 256 (195, 327) | 189 (104.5, 289.5) | 0.009 |
| Albumin (median, IQR) | 3 (2.3, 3.5) | 2.3 (1.9, 2.6) | <0.001 |
| Potassium (median, IQR) | 3.9 (3.5, 4.3) | 3.6 (3.2, 4.1) | 0.023 |
| Erythrocyte sedimentation rate (mm/h, median, IQR) | 35 (20, 48) | 41 (23, 56.8) | 0.331 |
| CRP (mg/L, median, IQR) | 1.6 (0.5, 4.1) | 6 (2.1, 9.7) | 0.002 |
| Treatment with cyclosporine or infliximab | 6/231 (2.6%) | 5/32 (15.6%) | 0.005 |
| Duration of hospital stay (days, median, IQR) | 7 (5, 10) | 13 (8, 19.8) | <0.001 |
CRP, serum C‐reactive protein; Hb, hemoglobin; n, number; IQR, interquartile range.