Table 3.
Comparisons of disease location and phenotype in Crohn's disease
| Vernier‐Massouille et al.36 (n = 281) | Van Limbergen et al.34 (n = 273) | de Bie et al.37 EUROKIDS Registry (n = 582) | Buderus et al.38 CEDATA‐GPGE Registry (n = 480) | Present study (n = 43) | ||
|---|---|---|---|---|---|---|
| Disease location† | L1 | 39 (14%) | 16 (5.9%) | 95 (16%) | 64 (13.3%) | 11 (26%) |
| L2 | 47 (17%) | 99 (36.3%) | 159 (27%) | 95 (19.8%) | 16 (37%) | |
| L3 | 194 (69%) | 138 (50.5%) | 307 (53%) | 300 (62.5%) | 16 (37%) | |
| L4‡ | 102 (36%) | 139 (50.9%) | 172 (30%) | 257 (53.5%) | 4 (9%) | |
| Disease phenotype§ | B1 | 71% | 249 (91.2%) | 959/1177¶ (82%) | 95.1% | 28 (65%) |
| B2 | 25% | 12 (4.4%) | 144/1177 (12%) | 2.8% | 11 (26%) | |
| B3 | 4% | 12 (4.4%) | 55 (5%) B2B3:19 (2%) | 2.1% | 4 (9%) |
†
L1: ileal, L2: colonic, L3: ileocolonic, L4: upper gastrointestinal involvement.
‡
L4 disease in addition to L1/L2 or L3.
§
B1: inflammatory, B2: stricturing, B3: penetrating.
¶
Information on disease behavior was available in 1177 cases.