Table 4.

RSV cases and RSV cases with severe outcomes by underlying medical condition (RSV cases and deceased RSV cases: week 01/2009‐20/2018; ICU‐admitted RSV cases and ventilated RSV cases: week 01/2013‐20/2018 original sentinel hospitals, week 01/2015‐20/2018 additional sentinel hospitals)

	N (%) of RSV cases n = 8761	N (%) of ICU‐admitted RSV cases n = 492	N (%) of ventilated RSV cases n = 185	N (%) of deceased RSV cases n = 25
Medical condition
Disorder of newborn related to slow fetal growth and fetal malnutrition	6 (0.1)	1 (0.2)	0	0
Extremely low birth weight (<1000 g)	9 (0.1)	3 (0.6)	3 (1.6)	0
Low birth weight (1000‐2499 g)	51 (0.6)	16 (3.4)	12 (6.5)	0
Extreme immaturity of newborn (<28 weeks)	8 (0.1)	3 (0.6)	3 (1.6)	0
Preterm newborn (28‐37 weeks)	62 (0.8)	21 (4.4)	14 (7.6)	0
Respiratory and cardiovascular disorder specific to the perinatal period	282 (3.5)	60 (12.7)	35 (19.0)	1 (4.0)
Congenital malformation of the heart	131 (1.6)	35 (7.4)	19 (10.3)	2 (8.0)
Congenital malformation of the great vessels	34 (0.4)	13 (2.8)	8 (4.4)	0
Congenital defect originating in perinatal period	61 (0.7)	14 (2.9)	8 (4.3)	1 (4.0)
Down syndrome	42 (0.5)	9 (1.9)	2 (1.1)	0
Sickle‐cell disorder	2 (0.0)	0	0	0
Cystic fibrosis	9 (0.1)	1 (0.2)	1 (0.5)	0
Vitamin D deficiency	13 (0.2)	3 (0.6)	3 (1.6)	1 (4.0)
Asthma	63 (0.7)	4 (0.8)	1 (0.5)	0
Chronic obstructive pulmonary disease (COPD)	43 (0.5)	11 (2.2)	8 (4.3)	3 (12.0)
Chronic pulmonary disease (excl. asthma and COPD)	54 (0.6)	5 (1.0)	5 (2.7)	2 (8.0)
Diabetes	62 (0.7)	16 (3.3)	12 (6.5)	4 (16.0)
Cardiovascular disease	222 (2.5)	69 (14.0)	47 (25.4)	15 (60.0)
Neurological disorders	167 (1.9)	34 (6.9)	18 (9.7)	8 (32.0)
Blood disease	129 (1.5)	33 (6.7)	25 (13.5)	9 (36.0)
Renal failure	65 (0.7)	22 (4.5)	14 (7.6)	6 (24.0)
Liver disease	24 (0.3)	8 (1.6)	5 (2.7)	5 (20.0)
Tuberculosis	2 (0.0)	1 (0.2)	1 (0.5)	0
Cancer	27 (0.3)	4 (0.8)	2 (1.1)	1 (4.0)
HIV/AIDS	0	0	0	0
Pregnancy	1 (0.0)	0	0	0