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. 2020 Oct 8;11:580380. doi: 10.3389/fendo.2020.580380

Table 3.

Association of maternal SCH and adverse pregnancy outcomes according to the 2017 ATA standard.

Outcomes ET, n (%) SCH2017, n (%) Unadjusted OR (95% CI) Model I OR (95% CI) Model II OR (95% CI)
ET SCH2017 P-value ET SCH2017 P-value ET SCH2017 P-value
PIH 27 (1.9%) 10 (6.6%) 1 (ref) 3.59 (1.70–7.57) 0.001 1 (ref) 5.12 (2.31–11.38) <0.001 1 (ref) 5.16 (2.30–11.54) <0.001
Preeclampsia 9 (0.6%) 8 (5.3%) 1 (ref) 8.61 (3.27–22.66) <0.001 1 (ref) 11.07 (3.80–32.24) <0.001 1 (ref) 10.91 (3.72–32.01) <0.001
GDM 277 (19.7%) 33 (21.7%) 1 (ref) 1.13 (0.75–1.70) 0.562 1 (ref) 1.21 (0.79–1.85) 0.376 1 (ref) 1.21 (0.79–1.85) 0.373
CS 505 (36%) 64 (42.1%) 1 (ref) 1.30 (0.92–1.82) 0.136 1 (ref) 1.62 (1.13–2.32) 0.009 1 (ref) 1.68 (1.16–2.42) 0.006
Preterm delivery 663 (47.2%) 82 (53.9%) 1 (ref) 1.31 (0.94–1.83) 0.116 1 (ref) 1.60 (1.12–2.29) 0.009 1 (ref) 1.65 (1.16–2.37) 0.006
Postpartum hemorrhage 22 (1.6%) 3 (2.0%) 1 (ref) 1.27 (0.37–4.28) 0.705 1 (ref) 1.08 (0.32–3.67) 0.907 1 (ref) 1.01 (0.29–3.48) 0.986
Placenta previa 19 (1.4%) 5 (3.3%) 1 (ref) 2.48 (0.91–6.74) 0.075 1 (ref) 3.81 (1.33–10.95) 0.013 1 (ref) 4.12 (1.42–11.97) 0.009
Placenta abruption 2 (0.1%) 0 (0%) 1 (ref) 0.996 1 (ref) 0.996 1 (ref) 0.996
Dystocia 19 (1.4%) 3 (2.0%) 1 (ref) 1.47 (0.43–5.02) 0.538 1 (ref) 1.45 (0.42–5.04) 0.560 1 (ref) 1.46 (0.42–5.09) 0.556
Low birth weight 42 (3%) 9 (5.9%) 1 (ref) 2.04 (0.97–4.28) 0.059 1 (ref) 2.25 (1.03–4.92) 0.042 1 (ref) 2.19 (1.00–4.80) 0.050
Preterm birth 663 (47.2%) 82 (53.9%) 1 (ref) 1.31 (0.94–1.83) 0.116 1 (ref) 1.60 (1.12–2.29) 0.009 1 (ref) 1.65 (1.16–2.37) 0.006
Macrosomia 68 (4.8%) 6 (3.9%) 1 (ref) 0.81 (0.34–1.89) 0.623 1 (ref) 0.82 (0.35–1.96) 0.662 1 (ref) 0.83 (0.35–2.00) 0.676
Fetal distress 26 (1.9%) 6 (3.9%) 1 (ref) 2.18 (0.88–5.37) 0.092 1 (ref) 2.32 (0.91–5.87) 0.077 1 (ref) 2.27 (0.89–5.78) 0.085
Fetal asphyxia 5 (0.4%) 0 (0%) 1 (ref) 0.996 1 (ref) 0.996 1 (ref) 0.996
Fetal deformities 14 (1.0%) 0 (0%) 1 (ref) 0.996 1 (ref) 0.996 1 (ref) 0.996
Stillbirth 10 (0.7%) 2 (1.3%) 1 (ref) 1.86 (0.40–8.56) 0.426 1 (ref) 1.48 (0.17–12.99) 0.724 1 (ref) 1.79 (0.20–16.12) 0.603
Total adverse 686 (48.9%) 85 (55.9%) 1 (ref) 1.33 (0.95–1.86) 0.099 1 (ref) 1.59 (1.09–2.31) 0.015 1 (ref) 1.61 (1.13–2.30) 0.009
maternal outcomes
Total adverse 723 (51.5%) 89 (58.6%) 1 (ref) 1.33 (0.95–1.87) 0.099 1 (ref) 1.69 (1.18–2.42) 0.004 1 (ref) 1.71 (1.19–2.44) 0.004
maternal outcomes

Model I, adjusted for maternal age, pregestational BMI, and gestation age; Model II, adjusted for maternal age, pregestational BMI, gestational age, number of previous pregnancies, number of previous births, primiparity, and gestational weight gain.