Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 8;11:524968. doi: 10.3389/fimmu.2020.524968

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Punta, Jennings, Melcher and Lise

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Estimates for the percentage of individuals in the general population predicted to HLA-present resistance mutation-associated neopeptides. For each mutation, the histogram illustrates the percentage of individuals in the 1000G dataset with an IBR < 0.5 (the IBR score is defined in Methods). Mutations on the x-axis are ordered according to decreasing percentages of individuals. We plot only mutations that have been observed in at least five patients (according to COSMIC). Colors indicate the different tumor tissues in which the resistance mutations have been observed; “haema&lymph” stands for hematopoietic and lymphoid tissue. Asterisks (*) mark mutations that have been shown to elicit T-cell responses in previous works (32–34).