Table 9.
Antiparasitic activity of Terminalia sp. against pathogenic parasites.
| Plant species/part | Extraction Procedure | Pathogenic parasites | Antiparasitic activity | Reference |
|---|---|---|---|---|
| Terminalia albida Scott-Elliot bark | Methanol extraction | P. falciparum | IC50 = 1.5 µg/mL | (Camara et al., 2019) |
| Methanol extraction | P. berghei |
In vivo, Terminalia albida Scott-Elliot treatment increased survival rates in P. berghei-infected mice. |
||
| Terminalia arjuna (Roxb. ex DC.) Wight & Arn. bark | Methanol in a Soxhlet’s apparatus | H. contortus ova | IC50 = 645.65 µg/mL | (Bachaya et al., 2009) |
| Methanol in a Soxhlet’s apparatus | H. contortus larva | IC50 = 467.74 µg/mL | ||
| Terminalia avicennioides Guill. & Perr. bark | Powder form | P. berghei | Inhibition of the malaria in infected mice | (Owoloye et al., 2019) |
| Terminalia catappa L. fruit | Ethanol extraction | P. posthuman | At 60 mg/ml; death time = 28 min | (Ingole et al., 2019) |
| Terminalia catappa L. leaf | Ethanol extraction | F. cobboldi | Motility inhibition within 3 h | (Anuracpreeda et al., 2016) |
| Butanol extraction | C. spatiosus | LC50 = 487.17 ppm. | (Minsakorn et al., 2019) | |
| Ethyl acetate extraction | P. falciparum | IC50 = 3.05 µg/mL | (Abiodun et al., 2011) | |
| Ethyl acetate extraction | T. brucei rhodesiense | IC50 = 7.80 µg/mL | (Abiodun et al., 2012) | |
| Terminalia ferdinandiana Exell fruit | Aqueous extraction | G. duodenalis | IC50 = 140 µg/mL | (Rayan et al., 2015) |
| Terminalia ferdinandiana Exell fruit pulp | – | G. duodenalis | LC50 = 1,150 µg/mL | (Cock and Rayan, 2020) |
| Terminalia mantaly H. Perrier leaf | Aqueous extraction | P. falciparum | IC50 = 2.09 µg/mL | (Mbouna et al., 2018) |
| Terminalia mantaly H. Perrier root | Methanol extraction | P. falciparum | IC50 = 7.01 µg/mL | (Mbouna et al., 2018) |
| Methanol extraction | P. falciparum | IC50 = 10.11 µg/mL | (Mbosso Teinkela et al., 2019) | |
| Hexane fraction | Trypanosoma brucei brucei | IC50 = 5.60 µg/mL | ||
| Terminalia mantaly H. Perrier stem | Methanol extraction | P. falciparum | IC50 = 3.63 µg/mL | (Mbouna et al., 2018) |
| Terminalia paniculata Roth root | Ethanol in a Soxhlet’s apparatus | P. posthuma | 25 mg/ml; death time = 87 min | (Acharyya and Prasenjit Bhuniya, 2019) |
| Terminalia superba Engl. & Diels leaf | Methanol in a Soxhlet’s apparatus | Trypanosoma brucei brucei | MIC = 1.6 mg/mL | (Antia et al., 2009) |
| Methanol extraction | P. falciparum | IC50 = 3.38 µg/mL | (Mbouna et al., 2018) |