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Knockdown of KCNQ1OT1 inhibits cardiomyocytes’ hypertrophy induced by Ang-II. (A) Immunofluorescence results for the effect of KCNQ1OT1 knockdown on cell surface areas. Scale bar: 200 microns. (B,C) mRNA or protein expression of ANF, BNP, and β-MHC by shKCNQ1OT1. *, P<0.05.
