Table 2.
Clinical characteristics of included patients.
| Variables | Total (n = 22,868) | Alive(n = 19,040) | Expired(n = 3,828) | p |
|---|---|---|---|---|
| Infection sites, No. (%) | < 0.001 | |||
| GI | 2843(12) | 2264(12) | 579(15) | |
| Cutaneous/soft tissue | 1903(8) | 1684(9) | 219(6) | |
| Gynecologic | 75(0) | 65(0) | 10(0) | |
| Other | 1500(7) | 1192(6) | 308(8) | |
| Pulmonary | 8751(38) | 7110(37) | 1641(43) | |
| Renal/UTI (including bladder) | 5212(23) | 4621(24) | 591(15) | |
| unknown | 2584(11) | 2104(11) | 480(13) | |
| MV, No. (%) | 5448(24) | 3807(20) | 1641(43) | < 0.001 |
| GCS | 13(9.81,15) | 13.72(10.12,15) | 10(7,13.8) | < 0.001 |
| Bilirubin (mg/dl), median (IQR) | 1.23(0.59,3.2) | 1.2(0.5,3.08) | 1.6(0.7,3.8) | < 0.001 |
| Creatinine (mg/dl), median (IQR) | 1.37(0.86,2.43) | 1.28(0.82,2.25) | 1.97(1.2,3.12) | < 0.001 |
| Platelet (), median (IQR) | 178(119,248) | 181(126,250) | 157(85,234) | < 0.001 |
| PaO2 (mmHg), median (IQR) | 85(63.26,115.57) | 86.33(64,116.28) | 79(60.36,110.94) | < 0.001 |
| MBP (mmHg), median (IQR) | 57(49,67) | 58(50,68) | 51(40,60) | < 0.001 |
| SOFA, median (IQR) | 8(6,10) | 7(6,9) | 10(8,12) | < 0.001 |
| Urine Output (ml/d), median (IQR) | 50(0,1000) | 100(0,1100) | 0(0,575) | < 0.001 |
| Temperature (℃), median (IQR) | 37.3(36.9,38.11) | 37.33(36.9,38.11) | 37.3(36.8,38.2) | < 0.001 |
| RR (/min), median (IQR) | 29(24,35) | 28(24,34) | 32(26,38) | < 0.001 |
| HR (/min), median (IQR) | 109(95,124.99) | 108(94,123) | 117(100.36,134) | < 0.001 |
| pH, median (IQR) | 7.35(7.27,7.41) | 7.36(7.29,7.42) | 7.3(7.2,7.38) | < 0.001 |
| Hematocrit (%), median (IQR) | 30.6(26.4,35) | 30.8(26.7,35.1) | 29.3(25.1,34.25) | < 0.001 |
| Albumin (mg/dl), median (IQR) | 2.5(2.1,2.9) | 2.5(2.1,2.9) | 2.3(1.9,2.71) | < 0.001 |
| BUN (mg/dl), median (IQR) | 28(17,46) | 26(16,43) | 40(26,59) | < 0.001 |
| Glucose (mg/dl), median (IQR) | 132(93,206) | 132(94,204) | 134(86,215) | 0.011 |
| Comorbidities, No. (%) | ||||
| AIDS | 66(0) | 50(0) | 16(0) | 0.152 |
| Hepatic failure | 463(2) | 320(2) | 143(4) | < 0.001 |
| lymphoma | 211(1) | 160(1) | 51(1) | 0.006 |
| Metastatic cancer | 748(3) | 530(3) | 218(6) | < 0.001 |
| leukemia | 338(2) | 240(1) | 98(3) | < 0.001 |
| immunosuppression | 1232(6) | 947(5) | 285(8) | < 0.001 |
| Cirrhosis | 611(3) | 416(2) | 195(5) | < 0.001 |
Characteristics expressed as median [IQR] unless specified otherwise.
Abbreviations: AIDS: acquired immune deficiency syndrome; IQR: interquartile range; SOFA: sequential organ failure assessment; MBP: mean blood pressure; RR: respiratory rate; GCS: Glasgow coma scale; MV: mechanical ventilation.