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. 2020 Oct 21;10:17874. doi: 10.1038/s41598-020-74906-z

Table 5.

Cross table showing the difference between optimal and actually received treatment.

Actually-received treatment Optimal treatment
Restricted fluid administration Liberal fluid administration
Day 1, No. (%)
Restricted fluid administration 10,728(47) 5,248(23)
Liberal fluid administration 4,410(19.3) 2,455(10.7)
Day 3, No. (%)
Restricted fluid administration 6,994(57.8) 2,374(19.6)
Liberal fluid administration 1,737(14.4) 992(8.2)
Day 5, No. (%)
Restricted fluid administration 2,549(43.1) 1,029(17.4)
Liberal fluid administration 1,746(29.5) 595(10.1)

The cross table shows the difference between the optimal treatment and the treatment that was received by the patient. For example, 10,728 patients received restricted fluid administration on day 1, which was consistent with the optimal treatment strategy. However, there were 4,410 patients who received liberal fluid administration, but they were expected to have better clinical outcome (survive to discharge) had they been treated with restricted fluid administration. In contrast, 5,248 patients received restricted fluid administration but would have had a better outcome had they received liberal fluid administration. Data on days 3 and 5 are interpreted in the same way.