Fig. 4. Induction of cell cycle arrest by colchicine (1) and compds 5c and 5i. COLO-357 (column a) and L929 (column b) cells were treated for 72 h with 5 μM of colchicine (1), 5c or 5i, respectively; trypsinized, permeabilized, and stained with PI. The percentage distribution of cells is indicated in the tables. Control cells are shown in grey.