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. 2020 Oct 13;2020:1931839. doi: 10.1155/2020/1931839

Table 5.

The potential mechanisms of acupuncture on CSAP.

Acupoints Beneficial effects Potential mechanisms Ref. #
PC6, HT5 Delay the process of plaque instability, reduce the incidence of malignant cardiovascular events Reduce the serum content of matrix metalloproteinase-9(MMP-9) [15]
PC6, HT5 Stabilize atherosclerotic plaque Decrease volume and the equivalent block of coronary artery calcified plaque (CACP) [23]
PC6 Vasodilatation, lowering blood pressure, inhibiting platelet adhesion and aggregation, maintaining normal cardiac output, controlling collateral circulation opening, adjusting tissue perfusion, and protecting myocardial perfusion Decrease endothelin (ET) and increase nitric oxide (NO) [16]
PC6, HT5 Improve the tension of the cardiac autonomic nervous system Increase heart rate variability (HRV) [24]
PC6 Improve the prognosis of CSAP Decrease neutrophil-lymphocyte ratio (NLR) [25]
PC6, RN17, HT6, SP10, LR3 Reduce inflammatory response Reduce the content of C-reactive protein (CRP) and tumor necrosis factor-α (TNF-α) [14]