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. 2020 Oct 21;3:593. doi: 10.1038/s42003-020-01304-6

Table 1.

Distribution of cancer spectrum in Cep55 transgenic mice.

No. Cancerous Lesions Cep55wt/wt(n = 40) Cep55wt/Tg(n = 40) Cep55Tg/Tg(n = 50) Cep55wt/wt vs Cep55Tg/Tg, Cep55wt/Tg vs Cep55Tg/Tg
# % # % # % p valuesa
1 Lymphoma 0 0 0 0 18 51.42 6.0 × 10−6 6.0 × 10−6
B-Cell Lymphoma 11 61.11 0.0010 0.0010
T-Cell Lymphoma 7 38.88 0.0159 0.0159
2 Undifferentiated sarcoma 0 0 0 0 9 25.71 0.0039 0.0039
Fibrosarcoma 3 33.33 0.2509 0.2509
Hemangiosarcoma 6 66.67 0.0317 0.0317
3 Bronchogenic adenocarcinoma 0 0 0 0 6 17.14 0.0317 0.0317
4 Hepatocellular Carcinoma 0 0 0 0 3 8.57 0.2509 0.2509
5 Gastric Carcinoma 0 0 0 0 5 14.28 0.0632 0.0632
6 Intestinal Papillary Carcinoma 0 0 0 0 3 8.57 0.2509 0.2509
7 Myelogenous Leukemia 0 0 0 0 7 20 0.0159 0.0159
8 Hepatic Hyperplasia (foci of cellular alteration) 1 2.22 4 8.69 12 34.28 0.0051 0.1019
9 Splenic follicular Hyperplasia 1 2.22 4 8.69 8 66.66 0.0398 0.5373
10 Endometrial Hyperplasia 0 0 0 0 4 33.33 0.1259 0.1259
11 Lipoma 0 0 0 0 1 2.9 1.0 1.0
12 Alveolar-Bronchiolar Adenoma 0 0 10 22.22 15 42.85 0.0001 0.6426
13 Hepatoma 0 0 2 4.34 2 5.7 0.5006 1.0

aP values: Fisher’s exact tests.