Table 1.
Population characteristics.
| Characteristic | Preeclampsia (N = 23) |
Controls (N = 50) |
p valuea |
|---|---|---|---|
| Median (IQR) or N (%) | Median (IQR) or N (%) | ||
| Maternal age | 32.3 (28.1–36.6) | 31.3(26.2–36.9) | 0.63 |
| Maternal race | 0.74 | ||
| Black | 6 (26.0%) | 14 (28.0%) | |
| Hispanic | 2 (8.7%) | 10 (20.0%) | |
| White, non-Hispanic | 15 (65.2%) | 26 (52.0%) | |
| Nullipara | 5 (22.0%) | 14 (28.0%) | 0.42 |
| Smoking | 4 (17.4%) | 10 (20.0%) | 0.79 |
| Married | 16 (70.0%) | 31 (62.0%) | 0.89 |
| Chronic hypertension | 3 (13.0%) | 0 (0.0%) | 0.009 |
| Chronic renal disease/proteinuria | 0 (0.0%) | 0 (0.0%) | NA |
| Pre pregnancy BMI | 24.6 (21.1–29.1) | 25.5 (22.5–30.0) | 0.74 |
| PE in prior pregnancy | 6 (33.3%) | 3 (8.3%) | 0.02 |
| Prior spontaneous PTB | 12 (66.7%) | 8 (22.2%) | 0.001 |
| Gestational age (weeks) at | |||
| Sampling | 11.3 (8.7–13.4) | 11.1 (9.6–13.7) | 0.97 |
| Delivery | 34.4 (32.0–35.3) | 39.4 (38.9–40.4) | < 0.001 |
| Birth metrics (g) | |||
| Birth weight | 2215 (1400–2811) | 3353 (3140–3725) | < 0.001 |
| Z-score | − 0.24 (− 1.1–0.6) | − 0.21 (− 0.7–0.8) | 0.45 |
| Infant gender | |||
| Female | 15 (65.2%) | 26 (52.0%) | 0.29 |
| Male | 8 (34.8%) | 24 (48.0%) | |
| Clinical characteristics | |||
| Median maximum systolic (mmHg) | 168 (147–180) | 112 (103–120) | < 0.001 |
| Median maximum diastolic (mmHg) | 96 (88–99) | 68 (61–73) | < 0.001 |
| Median 24 h protein (gram) | 581 (343–921) | NA | NA |
| Week of PE diagnosis | 32.4 (29.7–33.0) | NA | NA |
ap values calculated with Wilcoxon Rank Sum test, ANOVA, Chi Square test, or Fisher Exact test where appropriate.
NA not applicable/available.