Table 3.
Most frequently recurrent individual proteins distinguishing preeclampsia from controls in 100 multiplexed panels.
| Protein | Protein names | Biological function | Gene name | Frequency (%) |
|---|---|---|---|---|
| GP1BAa | Platelet glycoprotein Ib alpha chain | Blood coagulation | GP1BA | 79 |
| VTNCa | Vitronectin | Cell adhesion/migration | VTN | 57 |
| C1RLa | Complement C1r | Complement activation | C1RL | 49 |
| ZA2Ga | Zinc-alpha-2-glycoprotein | Cell adhesion | AZGP1 | 46 |
| APOC2 | Apolipoprotein C-II | Cholesterol homeostasis | APOC2 | 37 |
| APOH | Beta-2-glycoprotein 1 | Blood coagulation | APOH | 30 |
| JPH1 | Junctophilin-1 | Calcium ion transport | JPH1 | 28 |
| CO5 | Complement C5 | Complement activation | C5 | 16 |
| HEP2 | Heparin cofactor 2 | Blood coagulation | SERPIND1 | 16 |
| TPC11 | Trafficking protein complex subunit 11 | Golgi organization | TRAPPC11 | 14 |
| MBL2 | Mannose-binding protein C | Complement activation | MBL2 | 11 |
| AACT | Alpha-1-antichymotrypsin | Acute-phase response | SERPINA3 | 8 |
| DYH3 | Dynein heavy chain 3, axonemal | Cilium-dependent cell motility | DNAH3 | 7 |
| TSP1 | Thrombospondin-1 | Cell adhesion | THBS1 | 7 |
| CAPS1 | Calcium-dependent secretion activator 1 | Exocytosis | CADPS | 6 |
| APOD | Apolipoprotein D | Angiogenesis | APOD | 5 |
| LCAT | Phosphatidylcholine-sterol acyltransferase | Lipoproteins metabolism | LCAT | 5 |
aConstituents of highest scoring panel.