TABLE 2.

Combinatory effects of docetaxel and BX795 in PCa cells

Cell lines	Doc:BX Ratio	Combination index (CI)			Mean ± SD	Interactions
		ED50	ED75	ED90
DU145	1:250	0.522	0.277	0.151	0.317 ± 0.189	Synergism
	1:500	0.385	0.195	0.100	0.227 ± 0.145	Strong Synergism
	1:1000	0.359	0.170	0.082	0.204 ± 0.142	Strong Synergism
	1:2000	0.280	0.143	0.073	0.165 ± 0.105	Strong Synergism
	1:4000	0.256	0.134	0.071	0.154 ± 0.094	Strong Synergism
PC3	1:250	0.337	0.272	0.220	0.276 ± 0.058	Strong Synergism
	1:500	0.321	0.271	0.229	0.273 ± 0.046	Strong Synergism
	1:1000	0.344	0.279	0.226	0.283 ± 0.059	Strong Synergism
	1:2000	0.323	0.268	0.223	0.271 ± 0.050	Strong Synergism
	1:4000	0.240	0.222	0.205	0.222 ± 0.017	Strong Synergism
LNCaP	1:250	1.036	1.048	1.063	1.049 ± 0.013	Nearly additive
	1:500	1.056	1.074	1.097	1.076 ± 0.021	Nearly additive
	1:1000	1.033	0.930	0.846	0.936 ± 0.094	Nearly additive
	1:2000	1.000	0.905	0.833	0.913 ± 0.084	Nearly additive
	1:4000	0.991	0.905	0.880	0.925 ± 0.058	Nearly additive