Figure 2.

Regulatory roles of lncRNAs. A, LncRNAs recruit transcript factors or epigenetic regulators to gene promoter region and regulate gene transcription. B, LncRNAs competitively bind to miRNAs and inhibit the degradation of miRNAs target genes. C, LncRNAs interact with mRNA directly or enhance the interplay of mRNA and protein, which promotes the mRNA stability and increases gene expression. D, LncRNAs interact with protein and inhibit protein modification. LncRNAs interact with protein kinase and enhance protein modification