Table 1.

Osteogenic differentiation potential. All relative expression values of the osteogenic differentiation experiments are listed (mean ± SD; n = 7, measured in triplicates).

Gene.	Ctrl	Osteogenic Differentiated
ad Figure 3		CoCrMo	Polished	Porous	TiN	cpTi
Runx2 (Figure 3A)	1 ± 0.1	0.95 ± 0.2	0.84 ± 0.3	0.96 ± 0.1	1.00 ± 0.4	0.81 ± 0.3
Runx2 (Figure 3B)		1 ± 0.1	1.07 ± 0.2	0.77 ± 0.3	1.16 ± 0.3	0.69 ± 0.2 *
ALP (Figure 3A)	1 ± 0.1	5.17 ± 2.4 ***	5.92 ± 4.1 **	5.66 ± 3.3 ***	3.93 ± 1.8 ***	7.74 ± 2.8 ***
ALP (Figure 3B)		1 ± 0.1	1.62 ± 0.4*	1.26 ± 0.7	1.24 ± 0.3	1.93 ± 0.5 ***
Osteopontin (Figure 3A)	1 ± 0.1	10.63 ± 4.0 ***	4.38 ± 1.4 ***	5.73 ± 4.2 *	8.74 ± 3.2 ***	9.38 ± 5.6
Osteopontin (Figure 3B)		1 ± 0.1	0.68 ± 0.3 *	0.66 ± 0.2 **	1.05 ± 0.5	0.84 ± 0.7
Osteonectin (Figure 3A)	1 ± 0.1	1.26 ± 0.3	1.33 ± 0.5	0.77 ± 0.4	1.74 ± 0.4 **	1.44 ± 0.3 **
Osteonectin (Figure 3B)		1 ± 0.1	1.37 ± 0.5	0.79 ± 0.4	1.32 ± 0.4	1.04 ± 0.3
	Ctrl	Osteogenic Differentiated
ad Figure 4		CoCrMo	Polished	Porous	TiN	cpTi
Integrin α5 (Figure 4A)	1 ± 0.1	5.53 ± 1.2 ***	6.13 ± 2.0 ***	4.22 ± 1.8 **	6.83 ± 2.0 ***	7.03 ± 2.5 **
Integrin α5 (Figure 4B)		1 ± 0.1	1.41 ± 0.6	0.69 ± 0.2 *	1.35 ± 0.3 *	2,65 ± 0.8
Integrin β1 (Figure 4A)	1 ± 0.1	1.97 ± 0.3 ***	1.89 ± 0.6 **	1.17 ± 0.2	2.25 ± 0.4 ***	2.16 ± 0.5 **
Integrin β1 (Figure 3B)		1 ± 0.1	1.04 ± 0.3	0.59 ± 0.11 ***	1.17 ± 0.3	1.07 ± 0.3

***: p < 0.001; **: p < 0.01; *: p < 0.05.