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. 2020 Aug;15(2):125–131. doi: 10.2174/1574884714666190926124714

Table 3.

GBS infection: survivors and nonsurvivors in the PICU.

Sex Age (Year(s)) LOS in PICU
(Day(s))
Death Infection Site(s) Antibiotic Sensitivity Co-infection(s) Scarlet Fever PIM2 (%) A&E Admission Antibiotics Prior PICU Sepsis-1 Sepsis-2 Sepsis-3
M 1.03 1 Yes Blood culture Sensitive: penicillin
Resistant: clindamycin, erythromycin
Staphylococcus aureus No 76.9 Yes No Yes Yes Yes
M 1.45 135 Yes Lung tissue Sensitive: penicillin
Resistant: clindamycin, erythromycin
Pseudomonas species No 50.1 No No Yes Yes Yes
M 0.05 66 Yes CSF, blood culture and umbilical swab Sensitive: penicillin
Resistant: clindamycin, erythromycin
Klebsiella species No 55.5 Yes Yes Yes Yes Yes
M 0.08 3 No Blood culture Sensitive: penicillin, cotrimoxazole, erythromycin NA No 0.8% Yes No Yes Yes No
M 0.28 8 No CSF, blood culture Sensitive: penicillin, clindamycin, cotrimoxazole NA No 2.6% No Yes Yes Yes Yes
F 0.12 7 No CSF, blood culture Sensitive: penicillin
Resistant: clindamycin, erythromycin
Micrococcus species No 11.1% Yes Yes Yes Yes Yes
F 0.13 4 No Blood culture Sensitive: penicillin
Resistant: clindamycin, erythromycin
NA No 5.8% Yes No Yes Yes No
F 0.10 4 No Blood culture Sensitive: penicillin
Resistant: clindamycin, erythromycin
NA No 2.6% Yes Yes Yes Yes Yes

*Sepsis-1 defines as at least two of the following Systemic Inflammatory Response Syndrome (SIRS) clinical criteria are present: heart rate faster than 90 beats per min; respiratory rate faster than 20 breaths per min; leukocyte count greater than 12,000/μL or less than 4,000/μL; temperature less than 36°C or greater than 38°C, within the first 24 h of admission to PICU; Sepsis-2 defines as at least two of the SIRS criteria with confirmed infections; Sepsis-3 defines as at least two of the three clinical criteria in the pre-screening by Sequential Organ Failure Assessment (qSOFA) followed by at least two acute change of the complete SOFA score with confirmed infection [19, 20].