TABLE 1.
MICs of β-lactams.
| MICs (μg/ml) | |||||
| K. pneumoniae | E. coil | ||||
| BS407 | KP1559 | TOP10 | TOP10 | TOP10 | |
| β-Lactamsa | ΩblaKPC–55 | ΩblaKPC–2 | ΩblaKPC–55 | ΩblaKPC–2 | |
| Ampicillin | >32 | >32 | >32 | >32 | 4 |
| Aztreonam | 16 | >32 | 16 | >32 | 0.125 |
| Cefotaxime | 16 | >32 | 1 | 8 | <0.0625 |
| Ceftazidime | 16 | >32 | 8 | 32 | 0.25 |
| Ceftazidime + CAb | 16 | 4 | 0.5 | 0.25 | 0.25 |
| Ceftazidime + ABc | 0.125 | 2 | 0.5 | 0.25 | 0.25 |
| Cefoxitin | 32 | >32 | 2 | >32 | 2 |
| Cefepime | 8 | >32 | 1 | 8 | <0.0625 |
| Imipenem | 1 | 8 | 0.5 | 1 | 0.125 |
| Imipenem + CA | 0.5 | <0.0625 | 0.25 | 0.125 | 0.125 |
| Imipenem + AB | <0.0625 | <0.0625 | 0.5 | 0.25 | 0.25 |
| Meropenem | 2 | 16 | 0.25 | 1 | <0.0625 |
aAmpicillin (Sigma-Aldrich), aztreonam (Daehan New Pharm Co., Ltd., Gyeonggi-do, South Korea), cefotaxime (Aju Pharm Co., Ltd., Seoul, South Korea), ceftazidime (Sigma-Aldrich), cefoxitin (JW pharmaceutical, Co., Ltd., Seoul, South Korea), cefepime (Boryeong Pharmaceutical Co., Ltd., Seoul, South Korea), imipenem (MSD, Co., Inc., Kenilworth, NJ, United States), and meropenem (Sigma-Aldrich). bCA, clavulanic acid (Dong-A Pharmaceutical Co., Ltd., Seoul, South Korea). cAB, avibactam (BOC Sciences, Shirley, NY, United States).