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. 2020 Oct 8;11:561370. doi: 10.3389/fendo.2020.561370

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Copyright © 2020 Stelcer, Milecka, Komarowska, Jopek, Tyczewska, Szyszka, Lesniczak, Suchorska, Bekova, Szczepaniak, Ruchala, Karczewski, Wierzbicki, Szaflarski, Malendowicz and Rucinski.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of ENHO and GPR19 in clinical samples. (A) Profile of GPR19 expression in normal and tumor samples from GEPIA (Gene Expression Profiling Interactive Analysis) database. (B) Expression of ENHO and GPR19 in normal and tumor samples of human adrenal gland. (C) Kaplan–Meier survival analysis of 92 cases of adrenocortical carcinoma obtained from TCGA database. Expression data for ENHO and GPR19 were divided into group with high (above median) and low expression (bellow median). Statistical differences were determined by the Mann–Whitney U non-parametric test compared to normal adrenals. ***p < 0.001.