Table 3.
Hazard ratios and 95% CIs for the associations between beer, wine, or liquor drinks/day with the risk of gastric cardia adenocarcinoma and non-cardia adenocarcinoma in the NIH-AARP Diet and Health Study cohort (1995-2011)
| Cancer type | Alcohol consumption |
All1 | Male2 | Female2 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Case No. |
HR(95%CI) | Ptrend | Case No. |
HR(95%CI) | Ptrend | Case No. |
HR(95%CI) | Ptrend | ||
| Gastric cardia adenocarcinoma | Beer (drinks/ day) | |||||||||
| never | 257 | 1.00 | 0.04 | 213 | 1.00 | 0.02 | 44 | 1.00 | 0.3 | |
| >0-1 | 352 | 0.91(0.74-1.11) | 317 | 0.83(0.67-1.03) | 35 | 1.47(0.87-2.50) | ||||
| >1 | 53 | 0.74(0.53-1.04) | 52 | 0.71(0.50-0.99) | 1 | 0.92(0.13-6.76) | ||||
| Wine (drinks/ day) | ||||||||||
| never | 281 | 1.00 | 0.9 | 250 | 1.00 | 0.8 | 31 | 1.00 | 0.4 | |
| >0-1 | 327 | 0.95(0.78-1.15) | 288 | 0.94(0.76-1.16) | 39 | 1.01(0.57-1.78) | ||||
| >1 | 54 | 1.16(0.84-1.61) | 44 | 1.05(0.74-1.50) | 10 | 2.10(0.91-4.83) | ||||
| Liquor (drinks/ day) | ||||||||||
| never | 293 | 1.00 | 0.2 | 250 | 1.00 | 0.1 | 43 | 1.00 | 0.7 | |
| >0-1 | 271 | 0.98(0.80-1.20) | 244 | 1.06(0.85-1.32) | 27 | 0.59(0.33-1.04) | ||||
| >1 | 98 | 1.27(0.97-1.66) | 88 | 1.3(0.98-1.73) | 10 | 1.39(0.65-2.96) | ||||
| Gastric non-cardia adenocarcinoma | Beer (drinks/ day) | |||||||||
| never | 321 | 1.00 | 0.3 | 182 | 1.00 | 0.3 | 139 | 1.00 | 1.0 | |
| >0-1 | 333 | 1.03(0.85-1.25) | 272 | 1.03(0.81-1.29) | 61 | 1.03(0.73-1.47) | ||||
| >1 | 59 | 1.22(0.90-1.65) | 57 | 1.21(0.88-1.68) | 2 | 0.80(0.20-3.24) | ||||
| Wine (drinks/ day) | ||||||||||
| never | 330 | 1.00 | 0.2 | 228 | 1.00 | 0.5 | 102 | 1.00 | 0.2 | |
| >0-1 | 343 | 0.88(0.73-1.06) | 251 | 0.93(0.75-1.16) | 92 | 0.80(0.57-1.14) | ||||
| >1 | 40 | 0.90(0.64-1.28) | 32 | 0.96(0.65-1.43) | 8 | 0.79(0.37-1.68) | ||||
| Liquor (drinks/ day) | ||||||||||
| never | 364 | 1.00 | 0.06 | 243 | 1.00 | 0.06 | 121 | 1.00 | 0.7 | |
| >0-1 | 285 | 0.89(0.74-1.08) | 215 | 0.90(0.72-1.12) | 70 | 0.89(0.63-1.27) | ||||
| >1 | 64 | 0.80(0.60-1.07) | 53 | 0.76(0.55-1.06) | 11 | 1.04(0.54-2.01) | ||||
1
HRs come from Cox models adjusted for age, sex, ethnic group, health status, educational level, BMI, smoking status, self-reported diabetes, and healthy eating index 2010, and other types of alcohol drinking.
2
HRs come from Cox models adjusted for age, ethnic group, health status, educational level, BMI, smoking status, self-reported diabetes, and healthy eating index 2010 and other types of alcohol drinking.