Table 3.
Disaccharide Analysis of Human Placental CS and HS via LC–MSa
| CS disaccharide composition (%) |
HS disaccharide composition (%) |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| C | CH | UB | average | C | CH | UB | average | ||
| TriS | 0 | 0 | 0 | 0 | TriS | 3.6 | 4.4 | 0.5 | 2.8 ± 2.1 |
| 2S4S | 0.9 | 0.7 | 0.5 | 0.7 ± 0.2 | NS6S | 4.7 | 6.1 | 3.7 | 4.8 ± 1.2 |
| 2S6S | 0.8 | 0.7 | 0.6 | 0.7 ± 0.1 | NS2S | 7.2 | 14 | 19 | 13 ± 5.8 |
| 4S6S | 0.2 | 0.6 | 0 | 0.3 ± 0.3 | 2S6S | 0 | 0 | 0 | 0 |
| 6S | 26 | 24 | 31 | 27 ± 3.6 | NS | 19 | 27 | 29 | 25 ± 5.0 |
| 4S | 69 | 73 | 65 | 69 ± 3.7 | 6S | 3 | 3.5 | 4 | 3.5 ± 0.5 |
| 2S | 0 | 0 | 0 | 0 | 2S | 0 | 0 | 0 | 0 |
| 0S | 2.3 | 1.4 | 2.6 | 2.1 ± 0.6 | 0S | 62 | 46 | 44 | 50.7 ± 10 |
a
C is cotyledon, CH chorionic plate, and UB umbilical cord. The standard deviation was generated from differences among GAG compositions of three different regions. See Figure S3 for analytical error analysis.