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. 2020 Oct 15;12(10):1167–1176. doi: 10.4251/wjgo.v12.i10.1167

Table 3.

Comparison of sensitivity and specificity of serum markers for esophageal squamous cell carcinoma (%)

Variable HE4 CEA AFP CA19-9
Sensitivity 66.2 53.7 65.0 73.1
Specificity 85.7 82.1 66.0 60.7

HE4: Human epididymis protein 4; CEA: Carcinoma embryonic antigen; AFP: Alpha fetal protein; CA19-9: Carbohydrate antigen 19-9.