Table I.
Biochemical characteristics and analysis of the parameters of pre-diabetes patients without (n=74)/with (n=69) NAFLD.
| Parameter | Non NAFLD | NAFLD | P-value |
|---|---|---|---|
| Age (years) | 44.8±9.47 | 47.19±8.78 | 0.21 |
| Sex (% men) | 54.54 | 61.90 | 0.46 |
| Impaired glucose tolerance (%) | 20.00 | 21.42 | 0.86 |
| Impaired fasting glucose (%) | 47.27 | 40.47 | 0.50 |
| Impaired glucose tolerance + Impaired fasting glucose (%) | 32.20 | 38.09 | 0.55 |
| Waist circumference (cm) | 88.27±8.38 | 93.30±7.23 | 0.03a |
| Hip circumference (cm) | 94.46±8.16 | 98.39±7.72 | 0.04a |
| Waist to hip ratio | 88.35±8.13 | 93.20±7.24 | 0.02a |
| Body mass index (kg/m2) | 24.65±4.43 | 26.04±3.56 | 0.09 |
| Systolic blood pressure (mm Hg) | 112.74±14.50 | 131.45±33.02 | <0.01a |
| Diastolic blood pressure (mm Hg) | 75.74±17.58 | 88.97±23.62 | <0.01a |
| Fasting serum glucose (mmol/l) | 5.92±0.47 | 5.86±0.44 | 0.52 |
| Post-prandial serum glucose (mmol/l) | 7.76±1.58 | 8.21±1.59 | 0.16 |
| Glycosylated haemoglobin (%) | 5.85±0.65 | 5.76±0.45 | 0.44 |
| Total cholesterol (mg/dl) | 182.49±37.36 | 198.16±44.62 | 0.06 |
| Triglycerides (mg/dl) | 153.38±80.44 | 209.73±137.18 | <0.01a |
| HDL-cholesterol (mg/dl) | 38.49±7.58 | 34.35±7.61 | <0.01a |
| LDL-cholesterol (mg/dl) | 176.57±38.68 | 182.18±45.56 | 0.51 |
| Glutamate pyruvate transaminase (GPT) (IU/l) | 31.63±13.10 | 38.80±18.43 | 0.02a |
| Gama-glutamate transaminase (GGT) (IU/l) | 26.85±13.44 | 33.57±12.76 | 0.01a |
| Alkaline phosphatase (IU/l) | 105.23±29.44 | 108.07±23.93 | 0.61 |
| Glutamate oxaloacetate transaminase (GOT) (IU/l) | 26±8.91 | 35.69±22 | <0.01a |
| Fasting insulin (µIU/ml) | 13.4±3.38 | 17.19±7.07 | <0.01a |
| Postprandial insulin (µIU/ml) | 55.32±40.95 | 74.02±38.52 | 0.02a |
| HOMA%S | 58.90±21.55 | 45.65±14.20 | <0.01a |
| HOMA%B | 130.14±34.86 | 109.84±34.04 | <0.01a |
| HOMA-IR | 3.52±0.93 | 4.49±1.93 | <0.01a |
| Log leptin (ng/ml) | 0.86±0.40 | 1.28±0.18 | <0.01a |
aStatistically significant different results.