Table 1.
Associations of KLK mRNA expression with clinical parameters in advanced high-grade serous ovarian cancer
| Clinical parameters | KLK7a low/high |
KLK5 + KLK7b low/high |
|---|---|---|
| Age | p = 0.564 | p = 0.141 |
| ≤ 60 years | 40/18 | 26/32 |
| > 60 years | 56/25 | 46/34 |
| Residual tumor mass | p = 0.234 | p = 0.041 |
| 0 mm | 51/19 | 43/27 |
| > 0 mm | 44/23 | 29/37 |
| Ascites fluid volume | p = 0.261 | p = 0.244 |
| ≤ 500 ml | 54/24 | 45/32 |
| > 500 ml | 41/13 | 26/28 |
a Chi-square test (cut-off point: KLK7 = 67th percentile)
b Chi-square test (dichotomized into low level by KLK5 low and KLK7 low, and high level by KLK5 high and/or KLK7 high; cut-off point: KLK5 = 67th percentile, KLK7 = 67th percentile)
Due to missing values, numbers do not always add up to n = 139.