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. 2019 Jul 9;25(6):e12804. doi: 10.1111/adb.12804

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© 2019 The Authors. Addiction Biology published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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c‐Fos expression in hypothalamus, lateral habenula, and hippocampus following various withdrawal time points. Significant main effects for chronic intermittent ethanol (CIE), ethanol drinking (DRK), and interactions (CIE × DRK) are shown for each time point (^* P < .05, ^** P < .01, ^*** P < .001, ^**** P < .0001); significant post hoc comparisons are represented by letters above a given bar indicating to which other bar a significant difference was observed (eg, A = first bar, B = second bar)