Table 1.

Patients’ main characteristics at enrollment on clinical settings

Gender (M:F)	4:4
Age (years)	68 [63–75]
BMI (Kg/m2)	27 [26–28]
SAPS II at ICU admission	56 [53–71]
Days of intubation before study	3 [2–5]
PaO2/FiO2	208 [185–237]
PaCO2 (mmHg)	37 [37–40]
pH	7.42 [7.37–7.45]
FiO2 (%)	45 [41–49]
PEEP (cmH2O)	12 [10–14]
Driving pressure (cmH2O)a	8.5 [7.7–9.0]
Respiratory system compliance (ml/cmH2O) a	46 [42–59]
Outcome: survivors	6/8

Data expressed as median [IQR]

BMI body mass index, SAPSII simplified acute physiology score II, ICU intensive care unit, PaO₂/FiO₂ partial pressure of arterial oxygen on inspired fraction of oxygen ratio, PEEP positive end-expiratory pressure

^aMeasured at PEEP = 5cmH₂O