Table 2.
Distribution of genotype and allele among asthma patients and controls
Study author | Asthma cases | Healthy control | P-HWE | MAF | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
CC | CT | TT | C | T | CC | CT | TT | C | T | |||
Walley et al. [29] | 56 | 55 | 13 | 167 | 81 | 31 | 23 | 5 | 85 | 33 | 0/8 | 0/72 |
Hijazi et al. [30] | 5 | 25 | 54 | 35 | 133 | 9 | 31 | 60 | 49 | 151 | 0/1 | 0/245 |
Sandford et al. [31] | 146 | 78 | 9 | 370 | 96 | 100 | 41 | 2 | 241 | 45 | 0/33 | 0/842 |
Takabayashi et al. [32] | 6 | 43 | 51 | 55 | 145 | 10 | 39 | 51 | 59 | 141 | 0/53 | 0/295 |
Hakonarson et al. [33] | 73 | 20 | 1 | 166 | 22 | 67 | 25 | 2 | 159 | 29 | 0/85 | 0/845 |
Cui et al. [34] | 11 | 89 | 141 | 111 | 371 | 9 | 52 | 114 | 70 | 280 | 0/34 | 0/2 |
Basehore et al. (i) [16] | 153 | 72 | 8 | 378 | 88 | 181 | 59 | 5 | 421 | 69 | 0/94 | 0/859 |
Basehore et al. (ii) [16] | 22 | 77 | 69 | 121 | 215 | 29 | 119 | 121 | 177 | 361 | 0/97 | 0/329 |
Basehore et al. (iii) [16] | 43 | 55 | 18 | 141 | 91 | 55 | 59 | 16 | 169 | 91 | 0/97 | 0/65 |
Lee et al. [35] | 9 | 77 | 168 | 95 | 413 | 3 | 29 | 68 | 35 | 165 | 0/96 | 0/175 |
Park et al. [36] | 19 | 164 | 349 | 202 | 862 | 7 | 54 | 109 | 68 | 272 | 0/92 | 0/2 |
Wang et al. [37] | 29 | 42 | 22 | 100 | 86 | 21 | 26 | 15 | 68 | 56 | 0/22 | 0/548 |
Adjers et al. [38] | 106 | 103 | 34 | 315 | 171 | 189 | 164 | 48 | 542 | 260 | 0/18 | 0/675 |
Donfack et al. (i) [26] | 85 | 34 | 7 | 204 | 48 | 144 | 55 | 6 | 343 | 67 | 0/78 | 0/836 |
Donfack et al. (ii) [26] | 25 | 82 | 98 | 132 | 278 | 24 | 82 | 77 | 130 | 236 | 0/76 | 0/355 |
Zhang et al. (i) [27] | 4 | 47 | 101 | 55 | 249 | 3 | 45 | 109 | 51 | 263 | 0/5 | 0/162 |
Zhang et al. (ii) [27] | 11 | 35 | 30 | 57 | 95 | 16 | 43 | 41 | 75 | 125 | 0/4 | 0/375 |
Zhang et al. (iii) [27] | 50 | 31 | 6 | 131 | 43 | 66 | 30 | 7 | 162 | 44 | 0/17 | 0/786 |
Gervaziev et al. [39] | 16 | 75 | 18 | 107 | 111 | 18 | 43 | 7 | 79 | 57 | 0/01 | 0/58 |
Schubert et al. [40] | 143 | 78 | 10 | 364 | 98 | 189 | 74 | 7 | 452 | 88 | 0/93 | 0/837 |
Kabesch et al. [41] | 42 | 29 | 2 | 113 | 33 | 564 | 188 | 21 | 1316 | 230 | 0/26 | 0/851 |
Battle et al. [42] | 28 | 113 | 114 | 169 | 341 | 19 | 77 | 79 | 115 | 235 | 0/97 | 0/328 |
Hosseini-Farahabadi et al. [43] | 17 | 8 | 5 | 42 | 18 | 38 | 12 | 0 | 88 | 12 | 0/33 | 0/88 |
Kamali-Sarvestani et al. [44] | 139 | 6 | 4 | 284 | 14 | 93 | 18 | 1 | 204 | 20 | 0/9 | 0/91 |
Chiang et al. [45] | 1 | 19 | 147 | 21 | 313 | 7 | 34 | 70 | 48 | 174 | 0/31 | 0/216 |
Mak et al. [46] | 15 | 95 | 179 | 125 | 453 | 19 | 87 | 186 | 125 | 459 | 0/05 | 0/214 |
Attab et al. [47] | 31 | 9 | 0 | 71 | 9 | 33 | 7 | 0 | 73 | 7 | 0/54 | 0/912 |
De Faria et al. [48] | 38 | 41 | 9 | 117 | 59 | 67 | 108 | 27 | 242 | 162 | 0/1 | 0/599 |
Jiang et al. [49] | 0 | 8 | 5 | 8 | 18 | 1 | 9 | 3 | 11 | 15 | 0/13 | 0/423 |
Amirzargar et al. [50] | 0 | 59 | 0 | 59 | 59 | 10 | 129 | 0 | 149 | 129 | < 0.001 | 0/535 |
Daley et al. [51] | 476 | 155 | 13 | 1107 | 181 | 549 | 186 | 16 | 1284 | 218 | 0/95 | 0/854 |
Haller et al. [52] | 6 | 30 | 36 | 42 | 102 | 7 | 31 | 32 | 45 | 95 | 0/89 | 0/321 |
Rad et al. [53] | 46 | 18 | 0 | 110 | 18 | 42 | 23 | 0 | 107 | 23 | 0/08 | 0/823 |
Wu et al. [54] | 6 | 83 | 163 | 95 | 409 | 11 | 84 | 132 | 106 | 348 | 0/61 | 0/233 |
Beghe et al. [55] | 232 | 63 | 4 | 527 | 71 | 136 | 37 | 3 | 309 | 43 | 0/79 | 0/877 |
Bijanzadeh et al. [56] | 92 | 4 | 4 | 188 | 12 | 48 | 1 | 1 | 97 | 3 | < 0.001 | 0/97 |
Fance et al. [57] | 38 | 13 | 11 | 89 | 35 | 27 | 1 | 2 | 55 | 5 | < 0.001 | 0/916 |
Baye et al. (i) [28] | 267 | 130 | 16 | 664 | 162 | 233 | 61 | 4 | 527 | 69 | 0/99 | 0/884 |
Baye et al. (ii) [28] | 35 | 140 | 140 | 210 | 420 | 12 | 25 | 14 | 49 | 53 | 0/89 | 0/48 |
Daneshmandi et al. [58] | 63 | 15 | 3 | 141 | 21 | 94 | 26 | 4 | 214 | 34 | 0/2 | 0/862 |
Huang et al. [59] | 1 | 19 | 80 | 21 | 179 | 4 | 43 | 75 | 51 | 193 | 0/46 | 0/209 |
Hwang et al. [60] | 1 | 51 | 136 | 53 | 323 | 12 | 89 | 275 | 113 | 639 | 0/15 | 0/15 |
Chiang et al. [61] | 13 | 110 | 329 | 136 | 768 | 7 | 34 | 65 | 48 | 164 | 0/38 | 0/226 |
Micheal et al. [62] | 26 | 63 | 19 | 115 | 101 | 31 | 84 | 5 | 146 | 94 | < 0.001 | 0/608 |
Ricciardolo et al. [63] | 35 | 19 | 3 | 89 | 25 | 109 | 12 | 3 | 230 | 18 | < 0.001 | 0/927 |
Smolnikova et al. [64] | 36 | 28 | 0 | 100 | 28 | 39 | 11 | 0 | 89 | 11 | 0/38 | 0/89 |
Li et al. [65] | 17 | 150 | 324 | 184 | 798 | 21 | 144 | 338 | 186 | 820 | 0/26 | 0/184 |
Wang et al. [66] | 50 | 177 | 165 | 277 | 507 | 104 | 412 | 333 | 620 | 1078 | 0/17 | 0/365 |
Dahmani et al. [67] | 13 | 19 | 12 | 45 | 43 | 6 | 11 | 2 | 23 | 15 | 0/35 | 0/605 |
Li et al. [68] | 112 | 0 | 205 | 224 | 410 | 138 | 0 | 213 | 276 | 426 | < 0.001 | 0/393 |
Narozna et al. [69] | 117 | 55 | 5 | 289 | 65 | 133 | 53 | 3 | 319 | 59 | 0/37 | 0/843 |
Zhang et al. [68] | 8 | 11 | 19 | 27 | 49 | 17 | 13 | 5 | 47 | 23 | 0/34 | 0/671 |
Hussein et al. [70] | 42 | 5 | 1 | 89 | 7 | 8 | 13 | 4 | 29 | 21 | 0/73 | 0/58 |
Abood et al. [71] | 66 | 17 | 17 | 149 | 51 | 7 | 90 | 3 | 104 | 96 | < 0.001 | 0/52 |
Zhang et al. [72] | 7 | 13 | 17 | 27 | 47 | 11 | 15 | 3 | 37 | 21 | 0/51 | 0/637 |
P-HWE p-value for Hardy–Weinberg equilibrium, MAF minor allele frequency of control group