Table 3.
Comparison of clinicopathologic factors of early gastric cardiac with or without oesophageal invasion
| Clinicopathologic factor | Oesophageal invasion | Total | P value | |
|---|---|---|---|---|
| Without | With | |||
| Number | 48 | 22 (1–10 mm, 4.16 ± 2.82 mm) | 70 | NS |
| Gender | ||||
| Male | 37 (77.1) | 13 (59.1) | 50 (71.4) | NS |
| Female | 11 (22.9) | 9 (40.9) | 20 (28.6) | |
| M/F ratio | 3.36 | 1.44 | 2.50 | |
| Age (year) | ||||
| ≤ 40 | 0 (0) | 0 | 0 | NS |
| 41–69 | 35 (72.9) | 19 (86.4) | 54 (77.1) | |
| ≥ 70 | 13 (27.1) | 3 (13.6) | 16 (22.9) | |
| Average (SD) | 64.44 ± 7.57 | 63.14 ± 7.88 | 64.03 ± 7.63 | NS |
| Origin | ||||
| Gastric | 48 (100) | 22 (100) | 70 (100) | NS |
| Oesophagus | 0 (0) | 0 (0) | 0 (0) | |
| Metaplasia | ||||
| Without | 14 (29.2) | 6 (27.3)) | 20 (28.6) | NS |
| Columnar cell | 23 (47.9) | 11 (50.0) | 34 (48.6) | |
| Pancreatic | 10 (20.8) | 3 (13.6) | 13 (18.6) | |
| Goblet cell | 1 (2.1) | 2 (9.1) | 3 (4.3) | |
| Macroscopic feature | ||||
| I | 3 (6.3) | 2 (9.1) | 5 (7.1) | NS |
| IIa | 2 (4.2) | 0 (0) | 2 (2.9) | |
| IIb | 10 (20.8) | 6 (27.3) | 16 (22.9) | |
| IIc | 17 (35.4) | 6 (27.3) | 23 (32.9) | |
| III | 16 (33.3) | 8 (36.4) | 24 (34.3) | |
| I + IIa | 5 (10.4) | 2 (9.1) | 7 (10.0) | NS |
| IIb | 10 (20.8) | 6 (27.3) | 16 (22.9) | |
| IIc + III | 33 (68.8)31 | 14 (63.6) | 47 (67.1) | |
| Size (cm) | ||||
| ≤ 0.9 | 10 (20.8) | 2 (9.1) | 12 (17.1) | NS |
| 1–1.9 | 21 (43.8) | 5 (22.7) | 26 (37.1) | |
| 2–2.9 | 12 (25.0) | 8 (36.4) | 20 (28.6) | |
| > 3 | 5 (10.4) | 7 (31.8) | 12 (17.1) | |
| Invasion depth | ||||
| M2 | 7 (14.6) | 2 (9.1) | 9 (12.9)) | NS |
| M3 | 14 (29.2) | 5 (22.7) | 19 (27.1) | |
| SM1 | 7 (14.6) | 3 (13.6) | 10 (14.3) | |
| SM2 | 20 (41.7) | 12 (54.5) | 32 (45.7) | |
| Histology type | ||||
| Tubular adenocarcinoma | 32 (66.7) | 8 (36.4) | 40 (57.1) | < 0.05 |
| Papillary adenocarcinoma | 7 (14.6) | 6 (27.3) | 13 (18.6) | |
| Micropapillary adenocarcinomaa | 1 (2.1) | 0 (0) | 1 (1.4) | |
| Poorly cohesive carcinoma | 1 (2.1) | 1 (4.5) | 2 (2.8) | |
| Mucinous carcinoma | 1 (2.1) | 0 (0) | 1 (1.4) | |
| Mixed PCC and adenocarcinoma | 3 (6.3) | 3 (13.6) | 6 (8.6) | |
| Mixed mucinous and tubular adenocarcinoma | 1 (2.1) | 2 (9.1) | 3 (4.3) | |
| Neuroendocrine/medullary /adenosquamous/clear cell carcinoma | 2 (4.2) | 2 (9.1) | 4 (5.7) | |
| Differentiation | ||||
| Well | 13 (27.1) | 4 (18.2) | 17 (24.3) | NS |
| Moderate | 28 (58.3) | 14 (63.6) | 42 (60.0) | |
| Poorly | 7 (14.6) | 4 (18.2) | 11 (15.7) | |
| Lymphovascular invasion | ||||
| Absence | 42 (87.5) | 17 (77.3) | 59 (84.3) | NS |
| Presence | 6 (12.5) | 5 (22.7) | 11 (15.7) | |
| Perineural invasion | ||||
| Absence | 46 (95.8) | 21 (95.5) | 67 (95.7) | NS |
| Presence | 2 (4.2) | 1 (4.5) | 3 (4.3) | |
| Lymph node metastasis | ||||
| Absence | 43 (89.6) | 20 (90.9) | 63 (90.0) | NS |
| Presence | 5 (10.4)) | 2 (9.1) | 7 (10.0) | |
| N1 | 4 (8.3) | 1 (4.5) | 5 (7.1) | |
| N2 | 1 (2.1) | 0 (0) | 1 (1.4) | |
| N3 | 0 (0.0) | 1 (4.5) | 1 (1.4) | |
SD standard deviation, PCC poorly cohesive carcinoma, NS not significant