Table 1.

Participating study site settings and corresponding ethical boards that approved BFF-Dx

Country	Brazil	Gabon	Malawi
Institute	Instituto Nacional de Infectologia Evandro Chagas (INI), FIOCRUZ, Rio de Janeiro	Center of Medical Research Lambaréné (CERMEL)	Malawi Epidemiology and Intervention Research Unit (MEIRU)
Enrolment site	UPA Rocha Miranda, UPA Manguinhos and Family Health Clinics Armando Palhares	Clinical trials unit, CERMEL	MEIRU, Chilumba campus
Enrolment setting	Primary healthcare facility in an urban area (favela)	Hospital in a semirural setting	Primary healthcare facility in a rural setting
Enrolment period	October 2018 to July 2019	May 2019 to November 2019	April 2017 to April 2018
Main causes of fever (expected)	Circulation of arboviruses, including dengue, Zika and chikungunya viruses	Endemic Plasmodium falciparum, dengue virus and chikungunya virus	Endemic Plasmodium falciparum and possibly chikungunya virus

BFF-Dx, Biomarker for Fever-Diagnostic.