Table 3.

List of patient-answered questionnaires

Subgroup	Adults	Paediatrics
IBS	Demographic questionnaire	Demographics (exclusions apply)
	Disease specific
	IBS Severity Score	IBS Severity Score  Rome IV Diagnostic Questionnaire
	GI symptoms
	PROMIS Scale 5a (GI Belly Pain) PROMIS Scale 6a (GI Diarrhoea) PROMIS Scale 9a (GI Constipation) PROMIS Scale 13a (GI Gas and Bloating) Leeds Dyspepsia Questionnaire	PedsQL GI Symptoms Scale (stomach pain and hurt; discomfort when eating; heartburn and reflux; nausea and vomiting; gas and bloating; constipation; blood in BM; diarrhoea; worry about stomachaches; worry about BM)—age 5–17
	General Quality of Life
	Euro Quality of Life	Euro Quality of Life Youth—age 8–15  Euro Quality of Life 5 Level—age 16+
	Psychological
	Patient Health Questionnaire PROMIS-29 (Physical Function, Anxiety, Depression, Fatigue, Sleep Disturbance, Pain Interference and Intensity) Generalised Anxiety Disorder (GAD-7) Perceived Stress Scale Adverse Childhood Experiences Brief Resiliency Survey Pain Catastrophising Scale	PROMIS-25 (Physical Function Mobility; Anxiety; Depressive Symptoms; Fatigue; Peer Relations; Pain Interference)—age 5–17  Brief Resiliency Survey—age 12–17  Pain Catastrophising Scale—age 8–17  Revised Child Anxiety and Depression Scale—age 6–17
	Productivity
	Work Productivity and Activity Index
	Diet
	Food Frequency Questionnaire FODMAP Questionnaire	Food Frequency Questionnaire  FODMAP Questionnaire
IBD	Demographic Questionnaire	Demographics (exclusions apply)
	Disease specific
	Short IBD Symptom Inventory	IMPACT-III—age 9–17  PUCAI (UC); PCDAI (CD)
	GI symptoms
	PROMIS Scale 5a (GI Belly Pain) PROMIS Scale 6a (GI Diarrhoea) PROMIS Scale 9a (GI Constipation) PROMIS Scale 13a (GI Gas and Bloating) Leeds Dyspepsia Questionnaire	PedsQL GI Symptoms Scale (stomach pain and hurt; discomfort when eating; heartburn and reflux; nausea and vomiting; gas and bloating; constipation; blood in BM; diarrhoea; worry about stomachaches; worry about BM)—age 4–17
	General quality of life
	Euro Quality of Life	Euro Quality of Life Youth—age 8–15
	Psychological
	Patient Health Questionnaire PROMIS-29 (Physical Function, Anxiety, Depression, Fatigue, Sleep Disturbance, Pain Interference and Intensity) GAD-7 Perceived Stress Scale Adverse Childhood Experiences Brief Resiliency Survey Pain Catastrophising Scale	PROMIS-25 (Physical Function Mobility; Anxiety; Depressive Symptoms; Fatigue; Peer Relations; Pain Interference)—age 5–17  Brief Resiliency Survey—age 12–17  Pain Catastrophising Scale—age 8–17  Revised Child Anxiety and Depression Scale—age 6–17
	Productivity
	Work Productivity and Activity Index
	Diet
	Food Frequency Questionnaire FODMAP Questionnaire	Food Frequency Questionnaire  FODMAP Questionnaire
Healthy controls	Demographic Questionnaire	Demographics (exclusions apply)
	GI symptoms
	PROMIS Scale 5a (GI Belly Pain) PROMIS Scale 6a (GI Diarrhoea) PROMIS Scale 9a (GI Constipation) PROMIS Scale 13a (GI Gas and Bloating) Leeds Dyspepsia Questionnaire	PedsQL GI Symptoms Scale (stomach pain and hurt; discomfort when eating; heartburn and reflux; nausea and vomiting; gas and bloating; constipation; blood in BM; diarrhoea; worry about stomachaches; worry about BM)— age 5–17
	General quality of life
	Euro Quality of Life	Euro Quality of Life Youth—age 8–15  Euro Quality of Life 5 Level—age 16+
	Psychological
	Patient Health Questionnaire PROMIS-29 (Physical Function, Anxiety, Depression, Fatigue, Sleep Disturbance, Pain Interference and Intensity) GAD-7 Perceived Stress Scale Adverse Childhood Experiences Brief Resiliency Survey Pain Catastrophising Scale	PROMIS-25 (Physical Function Mobility; Anxiety; Depressive Symptoms; Fatigue; Peer Relations; Pain Interference)—age 5–17  Brief Resiliency Survey—age 12–17  Pain Catastrophising Scale—age 8–17  Revised Child Anxiety and Depression Scale—age 6–17
	Productivity
	Work Productivity and Activity Index
	Diet
	Food Frequency Questionnaire FODMAP Questionnaire	Food Frequency Questionnaire  FODMAP Questionnaire

BM, bowel movement; CD, Crohn's disease; FODMAP, fermentable oligo-di-monosacharides and polyols; GI, gastrointestinal; IBD, inflammatory bowel disease; IBS, irritable bowel syndrome; PCDAI, Pediatric Crohn's Disease Activity Index; PedsQL, Pediatric Quality of Life Inventory; PROMIS, Patient-Reported Outcomes Measurement Information System; PUCAI, Paediatric Ulcerative Colitis Activity Index; UC, ulcerative colitis.