Table 3.
Respiratory parameters of COVID-19 patients with treated with HFNC.
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | |
|---|---|---|---|---|---|
| Baseline SpO2 (%) | 88 | 87 | 89 | 85 | 75 |
| Baseline ABG analysis | pH 7.49 PCO2 32 mm Hg PO2 54 mm Hg HCO3– 24 mmol/l |
pH 7.50 PCO2 31 mm Hg PO2 56 mm Hg HCO3– 25 mmol/l |
pH 7.48 PCO2 34 mm Hg PO2 55 mm Hg HCO3– 26 mmol/l |
pH 7.50 PCO2 33 mm Hg PO2 41 mm Hg HCO3– 30 mmol/l |
pH 7.33 PCO2 66 mm Hg PO2 38 mm Hg HCO3– 41 mmol/l |
| Baseline PaO2/FiO2 |
257 | 266 | 261 | 195 | 180 |
| SpO2 (%) during CPAP or NIV |
87 | 85 | 89 | 83 | 81 |
| Oxygen flow rate (l/min) | 40 | 50 | 40 | 45 | 60 |
| SpO2 (%) after HFNC |
98 | 97 | 96 | 96 | 94 |
| ABG analysis after HFNC | pH 7.45 PCO2 32 mm Hg PO2 75.5 mm Hg HCO3– 23 mmol/l |
pH 7.46 PCO2 34 mm Hg PO2 75.7 mm Hg HCO3– 24 mmol/l |
pH 7.45 PCO2 37 mm Hg PO2 72 mm Hg HCO3– 26 mmol/l |
pH 7.47 PCO2 33 mm Hg PO2 70 mm Hg HCO3– 25 mmol/l |
pH 7.45 PCO2 59 mm Hg PO2 66.7 mm Hg HCO3– 38 mmol/l |
| PaO2/FiO2 after HFNC | 359 | 360 | 343 | 335 | 315 |
| ROX index 2 h-HFNC |
8.8 | 7.5 | 8.5 | 6.8 | 5.5 |
| ROX index 12 h-HFNC |
10.5 | 9.6 | 10.2 | 9.5 | 6.7 |
ABG, arterial blood gas; COVID-19, coronavirus disease 2019; CPAP, continuous positive airway pressure; HFNC, high flow nasal cannula; NIV, non-invasive mechanical ventilation.