Table 3.

Comparison of whole-genome sequences of these different passages of the K168-8Ac strain.

Gene	Single-nucleotide differences between different passages							Amino acid changes between different passages
	Position	VP*	KP§	P35	P50	P60	P70	Position*	VP*	KP§	P35	P50	P60	P70
VP2	421	A	A	A	A	G	G	141	N	N	N	N	D	D
VP2	676	A	A	G	G	G	G	226	T	T	A	A	A	A
VP3	85	C	C	T	T	T	T	29	H	H	Y	Y	Y	Y
VP3	718	A	G	G	G	G	G	240	N	D	D	D	D	D
2C	684	A	G	G	G	G	G	228	V	V	V	V	V	V

^*The earliest passage of K168-8Ac propagated in Vero cells.

^§The earliest passage of K168-8Ac propagated in human embryonic lung diploid cells.