Table 4.
Demographic and Clinical Characteristics in Traumatic Brain Injury Cohort by Six-month Mortality Status
| Variable | Non-survivors (n = 48) | Survivors (n = 109) | p |
|---|---|---|---|
| Age (Mean, SE) | 51.08 (2.29) | 33.54 (1.35) | < 0.001 |
| Sex (men, %) | 35 (72.92) | 92 (84.40) | 0.092 |
| Race, (n, %) | 0.607 | ||
| White | 45 (95.74) | 99 (91.67) | |
| Black | 2 (4.26) | 8 (7.41) | |
| Other | 0 (0) | 1 (0.93) | |
| Best in 24 h GCS (Median, IQR) | 6 (5–7) | 7 (6–8) | 0.028 |
| Maximum head AIS severity, (n, %) | 0.6353 | ||
| 2 | 0 (0.00) | 1 (0.94) | |
| 3 | 1 (2.08) | 4 (3.77) | |
| 4 | 7 (14.58) | 23 (21.70) | |
| 5 | 40 (83.33) | 77 (72.64) | |
| 6 | 0 (0.00) | 1 (0.94) | |
| ISS (Mean, SE) | 33.90 (1.48) | 33.78 (1.00) | 0.655 |
| Non-head ISS (Mean, SE) | 14.30 (1.79) | 12.89 (1.06) | 0.558 |
| Length of hospital stay (Mean, SE) | 12.53 (1.34) | 23.89 (1.23) | < 0.001 |
| Mechanism of injury, (n, %) | < 0.001 | ||
| MVA | 16 (35.56) | 56 (53.33) | |
| Motorcycle | 8 (17.78) | 23 (21.90) | |
| Fall | 18 (40.00) | 12 (11.43) | |
| Other | 3 (6.67) | 14 (13.33) | |
| CT injury type, (n, %) | |||
| SDH | 36 (75.00) | 66 (61.11) | 0.092 |
| SAH | 35 (72.92) | 71 (65.71) | 0.375 |
| IVH | 12 (25.00) | 30 (27.78) | 0.718 |
| EDH | 9 (18.75) | 13 (12.04) | 0.266 |
| DAI | 6 (12.50) | 38 (35.19) | 0.004 |
| Contusion | 27 (56.25) | 36 (33.33) | 0.007 |
| Other | 4 (8.33) | 5 (4.63) | 0.360 |
| Splenic injury, (n, %) | 4 (8.33) | 11 (10.09) | 0.730 |
| Abdominal injury, (n, %) | 15 (36.59) | 38 (39.18) | 0.775 |
| Thoracic injury, (n, %) | 10 (24.39) | 30 (30.93) | 0.439 |
| Extremity injury, (n, %) | 29 (60.42) | 62 (57.94) | 0.773 |
| RS2470152 genotype, (n, %) | 0.099 | ||
| CC | 5 (13.89) | 25 (28.74) | |
| TC | 22 (61.11) | 36 (41.38) | |
| TT | 9 (25.00) | 26 (29.89) |
SE, standard error; GCS, Glasgow Coma Scale; IQR, interquartile range; AIS, Abbreviated Injury Scale; ISS, Injury Severity Score; MVA, motor vehicle accident; SDH, subdural hematoma; SAH, subarachnoid hemorrhage; IVH, intraventricular hemorrhage; EDH, epidural hematoma; DAI, diffuse axonal injury.