Table 3.

Bacterial growth on agar plates with different concentrations of the five AMPs cultivated in anaerobic atmosphere. Concentrations between 0.125 µg/ml and 8 µg/ml of all peptides were tested. In addition, nisin concentrations up to 128 µg/ml were tested.

Species	Peptide [µg/ml]	0,125	0,25	0,5	1	2	4	8	16	32	64	128
Megasphaera sp.	Nisin	+	+	+	±	-	-	-	-	-	-	-
	Lactof	+	+	+	+	+	+	+
	Melit	+	+	+	+	+	+	+
	Para-1	+	+	+	+	+	+	+
	LL-37	+	+	+	+	+	+	+
P. micra	Nisin	+	+	+	+	+	+	±	-	-	-	-
	Lactof	+	+	+	+	+	+	+
	Melit	+	+	+	+	+	+	+
	Para-1	+	+	+	+	+	+	+
	LL-37	+	+	+	+	+	+	+
B. longum	Nisin	+	+	+	±	-	-	-	-	-	-	-
	Lactof	+	+	+	+	+	+	+
	Melit	+	+	+	+	+	+	+
	Para-1	+	+	+	+	+	+	+
	LL-37	+	+	+	+	+	+	+
A. israelii	Nisin	+	+	+	+	+	+	+	-	-	-	-
	Lactof	+	+	+	+	+	+	+
	Melit	+	+	+	+	+	+	+
	Para-1	+	+	+	+	+	+	+
	LL-37	+	+	+	+	+	+	+
A. naeslundii	Nisin	+	+	+	+	+	+	+	+	-	-	-
	Lactof	+	+	+	+	+	+	+
	Melit	+	+	+	+	+	+	+
	Para-1	+	+	+	+	+	+	+
	LL-37	+	+	+	+	+	+	+
A. odontolyticus	Nisin	+	+	+	+	+	+	+	-	-	-	-
	Lactof	+	+	+	+	+	+	+
	Melit	+	+	+	+	+	+	+
	Para-1	+	+	+	+	+	+	+
	LL-37	+	+	+	+	+	+	+
S. aureus	Nisin	+	+	+	+	+	+	+	+	+	+	-
	Lactof	+	+	+	+	+	+	+
	Melit	+	+	+	+	+	+	+
	Para-1	+	+	+	+	+	+	+
	LL-37	+	+	+	+	+	+	+
S. anginosus	Nisin	+	+	+	+	+	+	+	+	+	+	-
	Lactof	+	+	+	+	+	+	+
	Melit	+	+	+	+	+	+	+
	Para-1	+	+	+	+	+	+	+
	LL-37	+	+	+	+	+	+	+
S. constellatus ssp. con.	Nisin	+	+	+	+	+	+	+	+	+	-	-
	Lactof	+	+	+	+	+	+	+
	Melit	+	+	+	+	+	+	+
	Para-1	+	+	+	+	+	+	+
	LL-37	+	+	+	+	+	+	+
P. intermedia	Nisin	+	+	+	+	+	+	+	+	+	-	-
	Lactof	+	+	+	+	+	+	+
	Melit	+	+	+	+	+	+	+
	Para-1	+	+	+	+	+	+	+
	LL-37	+	+	+	+	+	+	+
A. johnsonii, A. oris, A. actinomycetemcomitans, A. parvulum, C. concisus, C. rectus, D. pneumosintes, E. corrodens, E. cloacae, E. faecalis, E. coli, F nucleatum (fusiforme, nucleatum, polymorphum, vincentii), P. gingivalis, P. loescheii, P. melaninogenica, P. nigrescens, S. flueggei, S. sputigena, S. exigua, S. mutans, V. parvula, C. albicans	Nisin	+	+	+	+	+	+	+	+	+	+	+
	Lactof	+	+	+	+	+	+	+
	Melit	+	+	+	+	+	+	+
	Para-1	+	+	+	+	+	+	+
	LL-37	+	+	+	+	+	+	+

‘+’ – growth categories ii, iii, iv; ‘-’ – growth category i; ‘±’ – growth category i on at least one agar plate in at least one experiment; ‘empty table element’ – not measured; ‘Lactof’ – Lactoferrin; ‘Melit’ – Melittin; ‘Para-1’ – Parasin-1

P. aeruginosa was not cultivated anaerobically.