Table 1.
Chinese guidelines for the pharmacological treatment of COVID-19.
| Type | Title | Publish Date | TCM | IFN-α | IFN-k | Lopinavir /Ritonavir | Ribavirin | Chloroquine | Hydroxy-chloroquine | Umifenovir | Other antivirus drugs | Tocilizumab |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| National guideline | Notifications on the adjustment of dosage of chloroquine phosphate for the treatment of novel coronavirus pneumonia [21] | 2020–02-28 | NA | NA | NA | NA | NA | Yes | NA | NA | NA | NA |
| Expert consensus for appropriate application of TCM for COVID-19 [22] | 2020–03-01 | Yes | NA | NA | NA | NA | NA | NA | NA | NA | NA | |
| Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (7th version) [23] | 2020–03-04 | Yes | Yes | No | Yes | Yes | Yes | No | Yes | No | Yes | |
| Province guidelines-Diagnosis and treatment | Hubei province: A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (3rd Edition) [24] | 2020–01-28 | Yes | Yes | No | Yes | No | No | No | Yes | Oseltamivir | No |
| Peking Union Medical College Hospital’s proposal for diagnosis and treatment of “novel coronavirus-infected pneumonia” (V2.0) [25] | 2020–01-30 | Yes | No | No | Yes | No | No | No | No | No | No | |
| Hubei province: A rapid advice guideline for diagnosis and treatment of COVID-19 (integrated version) [26] | 2020–02-01 | Yes | Yes | No | Yes | Yes | No | No | No | Remdesivir | No | |
| Shandong expert consensus on the diagnosis and treatment for COVID-19 [27] | 2020–02-20 | Yes | Yes | No | Yes | Yes | No | Yes | Yes | No | No | |
| Province guidelines-TCM | Shanghai expert consensus on the integrated treatment for novel coronavirus pneumonia [28] | 2020–02-20 | Yes | Yes | Yes | No | No | Yes | Yes | Yes | No | No |
| Shanghai: Protocol for the use of traditional Chinese medicine for the diagnosis and treatment of COVID-19 [29] | 2020–02-24 | Yes | NA | NA | NA | NA | NA | NA | NA | NA | NA | |
| Expert Consensus on Rational Drug Use in Clinical Practice for COVID-19 [30] | 2020–02-28 | Yes | NA | NA | NA | NA | NA | NA | NA | NA | NA | |
| Hubei province: Protocol on the use of traditional Chinese medicine for Epidemic prevention and control of COVID-19 [31] | 2020–02-29 | Yes | NA | NA | NA | NA | NA | NA | NA | NA | NA | |
| Shanxi province: Protocol for the use of traditional Chinese medicine of COVID-19 [32] | 2020–03-01 | Yes | No | No | No | No | No | No | No | No | No | |
| Guangdong province: Expert consensus on Chinese integrative medicine for Epidemic prevention and control of COVID-19 [33] | 2020–03-10 | Yes | Yes | No | Yes | Yes | Yes | No | Yes | No | Yes | |
| Province guidelines-Chloroquine phosphate for COVID-19 | Hubei province: Close monitoring the adverse effects of chloroquine phosphate for the treatment of novel coronavirus pneumonia [34] | 2020–02-21 | NA | NA | NA | NA | NA | Yes | NA | NA | NA | NA |
| Guangdong province: Expert consensus on chloroquine phosphate for COVID-19 [35] | 2020–03-04 | NA | NA | NA | NA | NA | Yes | NA | NA | NA | NA |
COVID: Coronavirus Disease; IFN: Interferons; NA: Not applicable; TCM: Traditional Chinese Medicine.