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. 2020 Oct 9;8(1):1829884. doi: 10.1080/20016689.2020.1829884

Table 1.

Feasibility assessment network for quantitative comparative analyses of 5-FU: exclusion criteria of trials identified from the SLR.

  • Non-approved interventions

  • No common comparator, leading to exclusion of some dose-ranging arms/trials

  • Interventions not meeting the dosing and treatment period recommendations

  • No surgery: exclusion of treatment arms assessing cryotherapy or laser (or trial, if all arms are excluded)

  • No combination: exclusion of treatment arms evaluating combination therapy (or trial, if all arms are excluded)

  • No prior treatment: exclusion of trials evaluating treatment efficacy when used after a defined prior treatmenta

aTrials included if one or more arms did not have prior treatment.