Table 7. Examples of information provided in serum analysis certificates from different manufacturers.

Manufacturer	Country	Purpose	Method of inactivation	Sterility, mycoplasmas, endotoxins	Testing for viruses	BSE risk
1	2	3	4	5	6	7
Life Technologies	USA	For in vitro diagnostics	Thermally inactivated	+	For antibodies to BVDV, BPV, BAV, BRSV, BTV, rabies virus, reovirus	The serum is obtained in accordance with procedures approved by the US Department of Agriculture
	Australia					N/a
					For cytopathic effect: IBR
					For the presence of a hemadsorbing agent: PI3
	Brazil				BVDV, IBR, PI3
HyClone	USA	N/a	Not inactivated	+	For antibodies to BVDV, BPV, BAV, BRSV, BTV, rabies virus, reovirus	The serum is obtained in accordance with procedures approved by the US Department of Agriculture. Complies with Ph. Eur. 2011 5.2.8
					For cytopathic effect: IBR	USA has a geographical BSE risk level III (EFSA) and a “negligible BSE risk” (OIE)
Atlas Biologicals	USA	For production. Not intended for therapeutic use	γ-Irradiated	+	For the presence of a hemadsorbing agent: PI3	The serum is obtained in accordance with procedures approved by the US Department of Agriculture. All source materials were obtained from healthy animals without detectable diseases, and were not combined with materials of the specified risk
SAFC	USA					Animals from whom the serum was collected, were tested by the USDA and deemed eligible for slaughter
	Australia		Not inactivated			Serum was not collected from cattle in countries with reported cases of BSE
Gibco	New Zealand	For in vitro diagnostics	Thermally inactivated	+	Same as above	N/a
MP Biomedicals	USA	Only for study	Thermally inactivated	+	BVDV, IBR, PI3
Sigma-Aldrich	Colombia	Manufacturing	Thermally inactivated	+	BVDV, IBR, PI3