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. 2020 Oct 22;15(10):e0240987. doi: 10.1371/journal.pone.0240987

Table 2. Clinical characteristics according to gender and FVC% predicted.

Men (n = 1,.266) Women (n = 1,635)
FVC% predicted Q1 (n = 313) FVC% predicted Q2-4 (n = 953) p FVC% predicted Q1 (n = 406) FVC% predicted Q2-4 (n = 1,229) p
FVC% predicted 77.1 (33.1–82.3) 93.4 (82.5–121.6) <0.001 79.4 (48.2–84.1) 95.8 (84.1–138.6) <0.001
Age (years) 64 (40–80) 55 (40–80) <0.001 61 (40–80) 55 (40–80) <0.001
Education (%) 0.001 <0.001
Elementary school graduated 26.5 18.3 40.6 29.5
Junior high school graduated 14.4 11.3 14.5 13.8
Senior high school graduated 29.1 31.2 28.6 32.1
College graduated 30.0 39.2 16.3 24.6
Household Income (x10,000 KRW) 353.2 ± 17.8 446.0 ± 10.0 <0.001 348.2 ± 15.1 406.7 ± 9.2 0.001
Smoking (%) 0.165 0.523
Non-smoker 19.2 19.1 93.1 92.0
Ex- smoker 53.0 47.6 3.2 2.9
Current smoker 27.8 33.3 3.7 5.0
Alcohol consumption (%) 0.003 0.004
None 26.2 17.6 46.8 37.8
1-3/week 58.1 67.4 50.7 60.0
≥ 4/week 15.7 15.0 2.5 2.2
Aerobic exercise (%) 44.1 46.3 0.514 35.0 42.2 0.010
Obesity (%) 52.1 37.9 <0.001 50.7 32.1 <0.001
Hypertension (%) 56.5 39.3 <0.001 48.3 31.2 <0.001
Diabetes (%) 28.4 13.9 <0.001 20.2 10.3 <0.001
Renal impairment (%) 7.0 3.5 0.010 6.2 2.6 0.002
Serum uric acid (mg/dL)
Unadjusted 5.7 (5.6–5.9) 5.7 (5.6–5.8) 0.645 4.6 (4.5–4.7) 4.3 (4.2–4.3) <0.001
Model 1 5.8 (5.6–5.9) 5.7 (5.6–5.8) 0.175 4.5 (4.5–4.6) 4.3 (4.2–4.4) <0.001
Model 2 5.8 (5.6–5.9) 5.7 (5.6–5.8) 0.159 4.5 (4.4–4.6) 4.3 (4.3–4.4) 0.006
Hyperuricemia (%)
Unadjusted 16.9 14.2 0.233 9.9 4.4 <0.001
Model 1 18.0 (14.0–22.1) 13.8 (11.5–16.2) 0.077 9.1 (6.8–11.4) 4.6 (3.4–5.9) 0.001
Model 2 17.6 (13.5–21.6) 14.0 (11.7–16.2) 0.136 7.9 (5.7–10.1) 5.0 (3.8–6.2) 0.025

Data are expressed as mean ± SEM or %, except FVC% predicted, age, serum uric acid, and hyperuricemia. FVC% predicted and age are expressed as median (minimum-maximum). Serum uric acid, and hyperuricemia are expressed as mean (95% CI). FVC, forced vital capacity.

Model 1: adjusted for age Model 2: adjusted for all variables