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. 2020 Oct 22;16(10):e1008876. doi: 10.1371/journal.ppat.1008876

Fig 3. Mxra8 binding to CHIKV E1 and E2.

Fig 3

Side view (A) and top view (B and C) of Mxra8 bound to E1 and E2. Mxra8 (purple) wraps around 1 E1 (gray)-E2 (blue) heterodimer, contacts a second heterodimer within the same spike, and makes contacts with a third heterodimer on the adjacent spike. Capsid proteins are pictured in red. Mxra8 engages the CHIKV spike structure in a complex quaternary epitope. Image generated with Chimera software using [21] as a reference (PDB: 6NK6). CHIKV, Chikungunya virus; Mxra8, matrix remodeling associated protein 8.