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. 2020 Oct 22;15(10):e0240710. doi: 10.1371/journal.pone.0240710

Table 2. Multilevel negative binomial regression analysis to determine the association between daily incident cases and temperature.

Mean Temperature (model 1)
IRR (95%CI) Unadjusted IRR (95%CI) Adjusted* Coefficient P value Z
Quartile 1 (-21º to 5.5º) Reference Reference
Quartile 2 (6 º to 10.5 º) 1.16 (0.91 to 1.48) 1.18 (0.92 to 1.52) 0.17 0.188 1.32
Quartile 3 (11 º to 18.5 º) 1.01 (0.73 to 1.41) 1.11 (0.78 to 1.59) 0.10 0.550 0.60
Quartile 4 (19 º to 36.5 º) 0.82 (0.50 to 1.36) 1.12 (0.67 to 1.88) 0.11 0.663 0.44
BCG vaccine 0.35 (0.18 to 0.66) 0.46 (0.25 to 0.87) -0.76 0.016 -2.41
Minimum Temperature (model 2)
IRR (95%CI) Unadjusted IRR (95%CI) Adjusted* Coefficient P value Z
Quartile 1 (-26º to 1º) Reference Reference
Quartile 2 (2º to 6 º) 0.71 (0.56 to 0.90) 0.72 (0.57 to 0.93) -0.32 0.011 -2.56
Quartile 3 (7 º to 13 º) 0.69 (0.49 to 0.98) 0.85 (0.59 to 1.24) -0.15 0.405 -0.83
Quartile 4 (14 º to 34 º) 0.55 (0.34 to 0.91) 0.77 (0.46 to 1.29) -0.25 0.329 -0.98
BCG vaccine 0.35 (0.18 to 0.66) 0.50 (0.27 to 0.94) -0.69 0.032 -2.15
Maximum Temperature (model 3)
IRR (95%CI) Unadjusted IRR (95%CI) Adjusted* Coefficient P value Z
Quartile 1 (-16º to 9º) Reference Reference
Quartile 2 (10º to 16 º) 1.25 (0.99 to 1.57) 1.29 (1.02 to 1.63) 0.25 0.034 2.12
Quartile 3 (17 º to 25 º) 1.25 (0.93 to 1.68) 1.37 (0.99 to 1.87) 0.31 0.051 1.95
Quartile 4 (26 º to 44 º) 0.89 (0.54 to 1.46) 1.22 (0.73 to 2.04) 0.19 0.448 0.76
BCG vaccine 0.35 (0.18 to 0.66) 0.45 (0.24 to 0.84) -0.79 0.013 -2.50

Abbreviations: IRR- Incident Rate Ratio (Ratio between two incidence densities (rate in the exposed divided by rate in unexposed); CI- Confidence Interval; BCG- Bacillus Calmette–Guérin

*Adjusted or total number of tests done for COVID-19 in each country