Skip to main content
. Author manuscript; available in PMC: 2020 Oct 22.
Published in final edited form as: Clin Cancer Res. 2009 Dec 15;16(1):240–248. doi: 10.1158/1078-0432.CCR-09-0986

Table 2.

Protein expression and prognosis

Antibody ADC, HR (95% CI) P SqCC, HR (95% CI) P NSCLC, HR (95% CI) P
p-AKT (P vs N) 2.75 (1.44-5.94) 0.001 1.57 (0.92-2.84) 0.093 2.02 (1.34-3.19) <0.001
PTEN (P vs N) 0.72 (0.34-1.86) 0.465 1.61 (0.71-4.64) 0.276 1.11 (0.63-2.2) 0.72
p-TSC2 (P vs N) 1.95 (0.81-3.95) 0.122 1.11 (0.06-5.26) 0.888 1.82 (0.81-3.47) 0.131
p-mTOR (P vs N) 1.09 (0.71-1.67) 0.669 0.99 (0.65-1.54) 0.999 1.01 (0.75-1.36) 0.913
p-S6 (P vs N) 1.68 (1.06-2.60) 0.025 1.36 (0.82-2.17) 0.221 1.5 (1.07-2.06) 0.016
p-eIF4E (P vs N) 1.8 (1.18-2.74) 0.006 1.55 (1.00-2.39) 0.048 1.68 (1.24-2.27) <0.001
p-ERK1/2 (P vs N) 1.12 (0.68-1.78) 0.621 1.3 (0.63-2.41) 0.443 1.2 (0.81-1.73) 0.346

NOTE: Univariate analysis.

Abbreviations: HR, hazard ratio; 95% CI, 95% confidence interval.