Table 3. Impact of lymphopenia on relapse-free survival (RFS) and overall survival (OS).

S.no.	References	Disease	Lymphopenia	Impact on RFS (p-value)	Impact on OS (p-value)
1	Ray-Coquard et al [10]	Sarcoma	GL	NE	0.05
2	Saroha et al [11]	Renal cell carcinoma	GL	NE	0.012
3	Ceze et al [12]	Colon cancer	GL	0.048	0.003
4	De Giorgi et al [13]	Breast cancer	GL	0.001	0.001
5	Ray-Coquard et al [10]	Non-Hodgkin lymphoma	GL	0.002	0.04
6	Tredan et al [14]	Breast cancer first relapse	CD4+ lymphopenia	NE	0.00001
7	Tredan et al [14]	Breast cancer > second relapse	CD4+ lymphopenia	0.183	0.086
8	De Angulo et al [15]	Ewing sarcoma	GL	NE	0.007
9	Indexed data	Head-and-neck cancer	GL	NE	0.11

RS = Relapse-free survival;

OS = Overall survival;

GL = Global lymphopenia;

NE = Not evaluated.