Table 1. Association between CYP4Z1 expression and studied clinicopathological features.
| Characteristic | CYP4Z1-positive n = 187 | CYP4Z1-negative n = 41 | p value |
|---|---|---|---|
| Age (years) | |||
| ≤50 (n = 135, 59.3%) | 109 (58.3%) | 26 (63.4%) | 0.244 |
| >50 (n = 93, 40.7%) | 78 (41.7%) | 15 (36.6%) | |
| Histological type | |||
| Invasive ductal carcinoma (n = 178, 80.8%) | 148 (83.1%) | 30 (16.9%) | 0.021 |
| Invasive lobular carcinoma (n = 13, 5.9%) | 13 (100%) | 0 (0%) | |
| Intra-ductal carcinoma (n = 14, 6.4%) | 12 (85.7%) | 2 (14.3%) | |
| Mucinous adenocarcinoma (n = 6, 2.7%) | 5 (83.3%) | 1 (16.7%) | |
| Invasive papillary carcinoma (n = 2, 1%) | 2 (100%) | 0 (0%) | |
| Lobular carcinoma in situ (n = 2, 1%) | 2 (100%) | 0 (0%) | |
| Invasive apocrine carcinoma (n = 2, 1%) | 2 (100%) | 0 (0%) | |
| Others: (n = 3, 1.5%) | 2 (66.6%) | 1 (33.3%) | |
| Histological grade | |||
| I (n = 16, 7%) | 11(2.8%) | 5 (12.2%) | 0.04 |
| II (n = 93, 40.7%) | 80 (44.2%) | 13 (31.7%) | |
| III (n = 119, 52.2%) | 96 (53%) | 23 (56.1%) | |
| Lymph node metastasis | |||
| Yes (n = 61, 26.8%) | 50 (82%) | 11 (18.0%) | 0.044 |
| No (n = 158, 69.3%) | 131 (82.9%) | 27 (17.1%) | |
| NA (n = 9, 3.9%) | |||
| Histological stage | |||
| 1 (n = 38, 16.7%) | 32 (84.2%) | 6 (15.8%) | 0.447 |
| 2 (n = 144, 63.2%) | 116 (87.6%) | 28 (12.4%) | |
| 3 (n = 37, 16.2%) | 33 (89.2%) | 4 (10.8%) | |
| NA (n=9, 3.9%) | |||