Table 2.
Differentially expressed host circRNAs in human following virus infection.
| Virus | Sample type | Name of circRNAs with differentially expressed | Expression level | Reference |
|---|---|---|---|---|
| HTNV | HTNV-infected HUVECs | hsa_circ_0000479 | Up-regulated | (Lu et al., 2020) |
| HBV | Blood and liver tissues from CHB patients, HBV-infected hepatoma cells | hsa_circ_0004812 | Up-regulated | (Zhang and Wang, 2020) |
| HBV | Liver biopsies from untreated CHB patients | hsa_circ_0005389 and hsa_circ_0000038 |
Upregulated | (Zhou et al., 2018) |
| hsa_circ_0000650 | Down-regulated | |||
| HIV | PBMC of HARRT-naive EHI patients | hsa_circ_0000711 hsa_circ_0006968 | EHI group compared with HC group： up-regulated | (Zhang et al., 2018) |
| PBMCs of HARRT-naive CHI patients | hsa_circ_0003863 hsa_circ_0049083 | CHI group compared with EHI group： up-regulated | ||
| IAV H1N1 | H1N1-infected A549 cells | hsa_circ-GATAD2A | Up-regulated | (Yu et al., 2019) |
| HCMV | HCMV latent-infected THP-1 cells | hsa_circ_0001445 hsa_circ_0001206 | Down-regulated | (Lou et al., 2019) |
| KSHV | KSHV-infected HUVECs, B cell line, MC116 | hsa_circ_0001400 hsa_circ_0001741 hsa_circ_0008311 hsa_circ_0005145 | Up-regulated | (Tagawa et al., 2018) |
| HSV-1 | HSV-1 infected KMB17 cells | hsa_circRNA3046 hsa_circRNA3683 hsa_circRNA6783 hsa_circRNA7752 hsa_circRNA7231 | Up-regulated | (Shi et al., 2018) |
HTNV, hantaan virus; HIV-1, human immunodeficiency virus type 1; IAV, influenza A virus; HSV-1, herpes simplex virus; HCs, healthy controls; PBMC, Peripheral blood mononuclear cell; HARRT, Highly Active Antiretroviral Therapy; EHI, early HIV infection; CHI, chronic HIV infection.