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5′ and 3′ terminal sequences of SARS-CoV-2, SARS-CoV and MERS-CoV genomes. At the genomic level, the three coronaviruses have homology. SARS-CoV-2 and SARS-CoV have 82% structural similarity, however, it is 50% between SARS-CoV-2 and MERS-CoV. This suggests that experience can be gained from SARS-CoV and MERS-CoV outbreaks, which is very meaningful for better control of SARS-CoV-2 epidemic.
