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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Arch Toxicol. 2020 Sep 1;94(10):3409–3420. doi: 10.1007/s00204-020-02839-7

Table 2.

Results for Principle Component Analysis of Whole-Brain R1

PCs (90%) PC1 PC2 PC3

%Var Regions* %Var Regions* % Var Regions*

MEDIAN 6 77% Superior temporal sulcus 6.4% Ventricles Corpus Collosum 2.8% Superior parietal gyrus Superior occipital gyrus
VARIANCE 25 41.6% Cerebral White Matter, Parieto-occipital, cingulate-marginalis 11% Cuneus Precuneus Corpus Collosum 4.9% Cerebellum White Matter Cerebellum Cortex Brainstem
SKEW 49 12.3% Superior circular insula sulcus Posterior lateral fissure 7.8% Cerebral White Matter Precentral superior sulcus Postcentral Sulcus 5% Superior Frontal Gyrus Cerebellum Cortex Temporal Medial Parahip gyrus
10-PERCENTILE 13 72.6% Parieto-occipital sulcus Temporal Sulcus Cingulate 4.8% Ventricles Blood Vessels 2.5% Precentral Gyrus Postcentral Gyrus Cerebellar White Matter
90-PERCENTILE 13 63.8% Parietal Occipital Sulcus Temporal sulcus Hippocampus 9.6% Cuneus gyrus Precuneus Gyri Corpus Collosum 3.9% Ventricles Paracentral gyrus, sulcus Optic Chiasm
*

Regions presented had high weightings in both right and left hemisphere

While superior temporal sulcus is the highest weighted, the difference amongst regions varied by less than 1.